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[采用两种鼻阻力测量技术测定健康受试者的鼻阻力]

[Determination of nasal resistance in healthy subjects using 2 technics of rhinomanometry].

作者信息

Ghaem A, Martineaud J P

出版信息

Bull Eur Physiopathol Respir. 1985 Jan-Feb;21(1):11-6.

PMID:3978285
Abstract

Transnasal pressure-flow relationship was studied by active rhinomanometry. Nasal resistance was determined by a microprocessor assisted technique during quiet inspiration in 106 adults (49 females and 57 males) and in 52 children (21 girls and 31 boys) in various circumstances. The study was performed 1) to calculate the airflow nasal resistance (R) in different subjects, 2) to determine the laminar (K1) and turbulent (K2) coefficients of flow in the upper airways according to Rohrer's equation: R = K1 + K2 V, and 3) to compare the results of anterior and posterior rhinomanometry. The results of the experiments show that 1) nasal resistance was constant during the nasal cycle and from one week to another in the same subjects; 2) nasal resistance were higher in females than in males, and higher in children than in adults depending on nose development; and 3) the nasal resistance measured by posterior rhinomanometry (RP) was approximately twice as by anterior rhinomanometry (RA) and the correlation was highly significant. The regression line was RA = 0.82 RP - 0.06 in kPa . 1(-1) . s (r = 0.998). Anterior rhinomanometry was easier to perform than posterior rhinomanometry and more useful for performing challenges of the nasal mucosa.

摘要

通过主动鼻阻力测量法研究经鼻压力-流量关系。在不同情况下,采用微处理器辅助技术,对106名成年人(49名女性和57名男性)和52名儿童(21名女孩和31名男孩)安静吸气时的鼻阻力进行了测定。该研究旨在:1)计算不同受试者的气流鼻阻力(R);2)根据罗勒方程R = K1 + K2V确定上呼吸道层流系数(K1)和湍流系数(K2);3)比较前鼻阻力测量法和后鼻阻力测量法的结果。实验结果表明:1)在鼻周期以及同一受试者的不同周期间,鼻阻力保持恒定;2)女性的鼻阻力高于男性,儿童的鼻阻力高于成年人,这取决于鼻子的发育情况;3)后鼻阻力测量法(RP)测得的鼻阻力约为前鼻阻力测量法(RA)的两倍,且相关性高度显著。回归方程为RA = 0.82 RP - 0.06(kPa·1⁻¹·s)(r = 0.998)。前鼻阻力测量法比后鼻阻力测量法更易于操作,并且对于进行鼻黏膜激发试验更有用。

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