Siewerdsen J H, Jaffray D A
Department of Radiation Oncology, William Beaumont Hospital, Royal Oak, Michigan 48073-6769, USA.
Med Phys. 1999 Aug;26(8):1624-41. doi: 10.1118/1.598657.
Spatial and temporal imaging characteristics of an amorphous silicon flat-panel imager (FPI) were investigated in terms relevant to the application of such devices in cone-beam computed tomography (CBCT) and other x-ray imaging modalities, including general radiography, fluoroscopy, mammography, radiotherapy portal imaging, and nondestructive testing. Specifically, issues of image lag (including the magnitude, spatial uniformity, temporal-frequency characteristics, and dependence upon exposure and frame time) and long-term image persistence ("ghosts") were investigated. As part of the basic characterization of the FPI, pixel dark signal and noise (magnitude, temporal stability, and spatial uniformity) as well as radiation response (signal size, linearity, gain, and reciprocity) were also measured. Image lag was analyzed as a function of frame time and incident exposure. First-frame lag (i.e., the relative residual signal in the first frame following readout of an exposure) was approximately 2-10%, depending upon incident exposure and was spatially nonuniform to a slight degree across the FPI; second-, third-, and fourth-frame lag were approximately 0.7%, 0.4%, and 0.3%, respectively (at 25% sensor saturation). Image lag was also analyzed in terms of the temporal-frequency-dependent transfer function derived from the radiation response, allowing a quantitative description of system components contributing to lag. Finally, the contrast of objects as a function of time following an exposure was measured in order to examine long-term image persistence ("ghosts"). Ghosts were found to persist up to 30 min or longer, depending upon the exposure and frame time. Two means of reducing the apparent contrast of ghost images were tested: (i) rapid scanning of the FPI at maximum frame rate, and (ii) flood-field exposure of the FPI; neither was entirely satisfactory. These results pose important considerations for application of FPIs in CBCT as well as other x-ray imaging modalities. For example in CBCT, the magnitude of image lag is such that significant artifacts in tomographic reconstructions may result if strategies are not adopted either to reduce or correct the lag between successive projections (e.g., rapid scanning between projections or iterative correction algorithms, respectively). Similarly, long-term image persistence may necessitate frequent recalibration of offset corrections.
针对非晶硅平板探测器(FPI)在锥束计算机断层扫描(CBCT)及其他X射线成像模式(包括普通放射摄影、荧光透视、乳腺摄影、放射治疗射野成像和无损检测)中的应用,研究了其空间和时间成像特性。具体而言,研究了图像滞后问题(包括幅度、空间均匀性、时间频率特性以及对曝光和帧时间的依赖性)和长期图像残留(“重影”)。作为FPI基本特性表征的一部分,还测量了像素暗信号和噪声(幅度、时间稳定性和空间均匀性)以及辐射响应(信号大小、线性度、增益和互易性)。分析了图像滞后与帧时间和入射曝光的函数关系。首帧滞后(即曝光读出后第一帧中的相对残留信号)约为2% - 10%,具体取决于入射曝光,并且在FPI上空间均匀性略有不足;第二帧、第三帧和第四帧滞后分别约为0.7%、0.4%和0.3%(在传感器饱和度为25%时)。还根据从辐射响应得出的时间频率相关传递函数分析了图像滞后,从而对导致滞后的系统组件进行定量描述。最后,测量了曝光后物体对比度随时间的变化,以检查长期图像残留(“重影”)。发现重影会持续长达30分钟或更长时间,具体取决于曝光和帧时间。测试了两种降低重影图像表观对比度的方法:(i)以最大帧速率对FPI进行快速扫描,以及(ii)对FPI进行泛光场曝光;但两种方法都不完全令人满意。这些结果对FPI在CBCT以及其他X射线成像模式中的应用提出了重要考虑因素。例如在CBCT中,图像滞后的幅度使得如果不采取策略来减少或校正连续投影之间的滞后(例如分别在投影之间进行快速扫描或采用迭代校正算法),断层重建中可能会产生明显伪影。同样,长期图像残留可能需要频繁重新校准偏移校正。