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耳蜗植入和听觉脑干植入受者的正电子发射断层扫描

Positron emission tomography in cochlear implant and auditory brain stem implant recipients.

作者信息

Miyamoto R T, Wong D, Pisoni D B, Hutchins G, Sehgal M, Fain R

机构信息

Department of Otolaryngology-Head and Neck Surgery, Indiana University School of Medicine, Indianapolis 46202, USA.

出版信息

Am J Otol. 1999 Sep;20(5):596-601.

PMID:10503581
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3482826/
Abstract

OBJECTIVE

The purpose of this study was to determine whether similar cortical regions are activated by speech signals in profoundly deaf patients who have received a multichannel cochlear implant (CI) or auditory brain stem implant (ABI) as in normal-hearing subjects.

STUDY DESIGN

Positron emission tomography (PET) studies were performed using a variety of discrete stimulus conditions. Images obtained were superimposed on standard anatomic magnetic resonance imaging (MRI) for the CI subjects. The PET images were superimposed on the ABI subject's own MRI.

SETTING

Academic, tertiary referral center.

PATIENTS

Five subjects who have received a multichannel CI and one who had received an ABI.

INTERVENTION

Multichannel CI and ABI.

MAIN OUTCOME MEASURE

PET images.

RESULTS

Similar cortical regions are activated by speech stimuli in subjects who have received an auditory prosthesis.

CONCLUSIONS

Neuroimaging provides a new approach to the study of speech processing in CI and ABI subjects.

摘要

目的

本研究旨在确定接受多通道人工耳蜗植入（CI）或听觉脑干植入（ABI）的极重度聋患者，其大脑皮质被言语信号激活的区域是否与听力正常的受试者相似。

研究设计

使用多种离散刺激条件进行正电子发射断层扫描（PET）研究。对于接受CI的受试者，将获得的图像叠加在标准解剖磁共振成像（MRI）上。PET图像则叠加在接受ABI受试者自身的MRI上。

研究地点

学术性三级转诊中心。

患者

5名接受多通道CI的受试者和1名接受ABI的受试者。

干预措施

多通道CI和ABI。

主要观察指标

PET图像。

结果

接受听觉假体的受试者，其言语刺激可激活相似的大脑皮质区域。

结论

神经影像学为研究CI和ABI受试者的言语处理提供了一种新方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/231f/3482826/ea67b4050005/nihms410777f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/231f/3482826/350e31c3fd51/nihms410777f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/231f/3482826/263c8213d5dd/nihms410777f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/231f/3482826/729ca5c4c32a/nihms410777f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/231f/3482826/ea67b4050005/nihms410777f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/231f/3482826/350e31c3fd51/nihms410777f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/231f/3482826/263c8213d5dd/nihms410777f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/231f/3482826/729ca5c4c32a/nihms410777f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/231f/3482826/ea67b4050005/nihms410777f4.jpg

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