Faculdade de Medicina de Ribeirão Preto (FM-RP), Universidade de São Paulo (USP), São Paulo, SP, Brazil.
Universidade Estadual Paulista (UNESP), São Paulo, SP, Brazil.
Braz J Otorhinolaryngol. 2015 Mar-Apr;81(2):126-32. doi: 10.1016/j.bjorl.2014.10.001. Epub 2014 Oct 18.
Behavioral and electrophysiological auditory evaluations contribute to the understanding of the auditory system and of the process of intervention.
To study P300 in subjects with severe or profound sensorineural hearing loss.
This was a descriptive cross-sectional prospective study. It included 29 individuals of both genders with severe or profound sensorineural hearing loss without other type of disorders, aged 11 to 42 years; all were assessed by behavioral audiological evaluation and auditory evoked potentials.
A recording of the P3 wave was obtained in 17 individuals, with a mean latency of 326.97ms and mean amplitude of 3.76V. There were significant differences in latency in relation to age and in amplitude according to degree of hearing loss. There was a statistically significant association of the P300 results with the degrees of hearing loss (p=0.04), with the predominant auditory communication channels (p<0.0001), and with time of hearing loss.
P300 can be recorded in individuals with severe and profound congenital sensorineural hearing loss; it may contribute to the understanding of cortical development and is a good predictor of the early intervention outcome.
行为和电生理听觉评估有助于了解听觉系统和干预过程。
研究严重或极重度感音神经性听力损失患者的 P300。
这是一项描述性的、前瞻性的、横断面研究。共纳入 29 名无其他类型疾病的 11 至 42 岁的男女两性严重或极重度感音神经性听力损失患者，所有患者均接受行为听力学评估和听觉诱发电位检查。
17 名患者记录到 P3 波，潜伏期的平均值为 326.97ms，振幅的平均值为 3.76V。潜伏期与年龄有关，振幅与听力损失程度有关，两者差异均有统计学意义。P300 结果与听力损失程度（p=0.04）、主要听觉交流通道（p<0.0001）和听力损失时间有显著相关性。
P300 可在严重和极重度先天性感音神经性听力损失患者中记录，它可能有助于了解皮质发育情况，是早期干预结果的良好预测指标。
