具有绒毛膜癌特征的乳腺癌：一例伴有细胞病理学细节的病例报告。

Breast cancer with choriocarcinomatous features: A case report with cytopathologic details.

作者信息

Murata T, Ihara S, Nakayama T, Nakagawa S I, Higashiguchi T, Imai T, Nakano H, Shiraishi T, Kuroda M, Moriya T

机构信息

Departments of Pathology and Clinical Laboratories, JA Suzuka Hospital, Japan.

出版信息

Pathol Int. 1999 Sep;49(9):816-9. doi: 10.1046/j.1440-1827.1999.00940.x.

DOI:10.1046/j.1440-1827.1999.00940.x

PMID:10504554

Abstract

A case of breast cancer with choriocarcinomatous features (BCCF) is reported. The patient was a 38-year-old Japanese female with a long history of schizophrenia. Her nursing staff noticed a palpable mass in her right breast, which showed rapid growth. Following cytopathologic confirmation of a malignant breast tumor, she underwent mastectomy with ipsilateral axillary lymph node dissection. Histologic examination revealed BCCF, which was positive for placental alkaline phosphatase and human chorionic gonadotropin (HCG) by immunohistochemistry. The serum HCG level was high. She died 7 months postoperatively, with multiple metastases of BCCF to the chest wall, lung and liver.

摘要

报告了一例具有绒毛膜癌特征的乳腺癌（BCCF）。患者为一名38岁的日本女性，有长期精神分裂症病史。她的护理人员注意到其右乳有一个可触及的肿块，且生长迅速。在细胞病理学确诊为恶性乳腺肿瘤后，她接受了乳房切除术及同侧腋窝淋巴结清扫术。组织学检查显示为BCCF，免疫组化显示胎盘碱性磷酸酶和人绒毛膜促性腺激素（HCG）呈阳性。血清HCG水平很高。她术后7个月死亡，BCCF已转移至胸壁、肺和肝脏。