具有绒毛膜癌特征的乳腺癌：病例报告及文献复习

Breast carcinomas with choriocarcinomatous features: case reports and review of the literature.

作者信息

Erhan Yildiz, Ozdemir Necmettin, Zekioglu Osman, Nart Deniz, Ciris Metin

机构信息

Department of Pathology, Ege University School of Medicine, Bornova, Izmir, Turkey.

出版信息

Breast J. 2002 Jul-Aug;8(4):244-8. doi: 10.1046/j.1524-4741.2002.08411.x.

DOI:10.1046/j.1524-4741.2002.08411.x

PMID:12100118

Abstract

Breast cancer with choriocarcinomatous features is rare. This report describes four cases of breast cancer with choriocarcinomatous features. The tumor cells were positive for human placental lactogen (hPL) and human chorionic gonadotropin (hCG) by immunohistochemistry. The cases reported in the literature had a poor prognosis and the patients died within a few months after the diagnosis. In this series, two cases were lost to follow-up, but the other two have had disease-free survival for 2 and 4 years, respectively.

摘要

具有绒毛膜癌特征的乳腺癌很罕见。本报告描述了4例具有绒毛膜癌特征的乳腺癌病例。通过免疫组织化学检测，肿瘤细胞中人胎盘催乳素（hPL）和人绒毛膜促性腺激素（hCG）呈阳性。文献报道的病例预后较差，患者在诊断后几个月内死亡。在本系列病例中，2例失访，但另外2例分别无病生存了2年和4年。