尼日利亚拉各斯一家综合医院微生物的抗生素敏感性
Antibiotic susceptibility of microorganisms at a general hospital in Lagos, Nigeria.
作者信息
Odusanya O O
机构信息
Department of Community Health & Primary Care, Lagos State University College of Medicine, Ikeja, Nigeria.
出版信息
J Natl Med Assoc. 2002 Nov;94(11):994-8.
OBJECTIVE
To determine susceptibility patterns of microorganisms to antibiotics in a large general hospital in Lagos, Nigeria.
METHODS
Clinical samples received in the laboratory were processed according to standard methods. Susceptibility to antibiotics was done using a disk diffusion technique.
RESULTS
Five hundred and fifty-one samples from urine, wound, reproductive tract and other body fluids were analysed. The most frequently isolated pathogens (n=586) were Staphylococcus aureus, Escherichia coli and Klebsiella pneumoniae. Most of the organisms were sensitive to ciprofloxacin, perfloxacin, cefuroxime, ceftriaxone and azithromycin but were resistant to ampicillin, cotrimoxazole and penicillin. Pseudomonas aeruginosa was multi-resistant. The susceptibility pattern obtained at this hospital is similar to what obtains in teaching hospitals in Nigeria.
CONCLUSION
Microorganisms isolated at this hospital are more sensitive to newer antibiotics.
目的
确定尼日利亚拉各斯一家大型综合医院中微生物对抗生素的敏感性模式。
方法
实验室收到的临床样本按照标准方法进行处理。使用纸片扩散法检测对抗生素的敏感性。
结果
对来自尿液、伤口、生殖道及其他体液的551份样本进行了分析。最常分离出的病原体（n = 586）为金黄色葡萄球菌、大肠杆菌和肺炎克雷伯菌。大多数微生物对环丙沙星、培氟沙星、头孢呋辛、头孢曲松和阿奇霉素敏感，但对氨苄西林、复方新诺明和青霉素耐药。铜绿假单胞菌具有多重耐药性。该医院获得的敏感性模式与尼日利亚教学医院的情况相似。
结论
该医院分离出的微生物对新型抗生素更敏感。
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