Häkkänen H, Summala H, Partinen M, Tiihonen M, Silvo J
Department of Psychology, University of Helsinki, Finland.
Sleep. 1999 Sep 15;22(6):798-802. doi: 10.1093/sleep/22.6.798.
This study focused on eyeblink duration as a measure of sleepiness in on-road driving and on the driving performance of professional bus drivers with polysomnographically confirmed mild obstructive Sleep Apnea Syndrome (OSAS). Ten bus drivers with OSAS and their matched controls participated in the study. The Maintenance of Wakefulness Test (MWT) and a monotonous on-road driving task were completed. Eyeblink duration and frequency and speed control were measured while driving. Lane-keeping was evaluated by the supervisor in the car. Subsequent to these tasks, drivers with OSAS received continuous positive airway pressure treatment (nasal CPAP). After nine weeks of treatment, the tasks were repeated. Prior to treatment the average blink duration in the driving task was significantly longer and sleep latency in the MWT was significantly shorter for bus drivers with OSAS than for controls (mean blink duration 82.3 ms; 51.9 ms and mean sleep latency 23.2 min; 35.4 min), indicating increased daytime sleepiness. Subsequent to treatment both measures in drivers with OSAS decreased to the level of the controls. Treatment effects in MWT and blink duration in on-road driving also correlated significantly. No significant differences between the groups appeared in average blink frequency or driving performance in terms of maintenance of speed. No significant lane drifting appeared either. These results support earlier findings on blink duration as an indicator of increased sleepiness and have important implications for those involved in the transport technological industry. The findings also suggest that nasal CPAP treatment is effective in reducing excessive daytime sleepiness.
本研究聚焦于眨眼持续时间,将其作为衡量道路驾驶中困倦程度的指标,并研究了经多导睡眠图确诊患有轻度阻塞性睡眠呼吸暂停综合征(OSAS)的职业巴士司机的驾驶表现。十名患有OSAS的巴士司机及其匹配的对照组参与了该研究。完成了清醒维持测试(MWT)和单调的道路驾驶任务。在驾驶过程中测量眨眼持续时间、频率和速度控制。由车内的监督员评估车道保持情况。在这些任务之后,患有OSAS的司机接受持续气道正压通气治疗(鼻持续气道正压通气)。经过九周的治疗后,重复这些任务。治疗前,患有OSAS的巴士司机在驾驶任务中的平均眨眼持续时间明显更长,在MWT中的睡眠潜伏期明显更短,相比对照组(平均眨眼持续时间82.3毫秒;51.9毫秒,平均睡眠潜伏期23.2分钟;35.4分钟),表明白天困倦感增加。治疗后,患有OSAS的司机的这两项指标均降至对照组水平。MWT中的治疗效果与道路驾驶中的眨眼持续时间也显著相关。两组在平均眨眼频率或速度维持方面的驾驶表现上没有显著差异。也没有出现明显的车道偏移。这些结果支持了早期关于眨眼持续时间作为困倦感增加指标的研究发现,对运输技术行业的相关人员具有重要意义。研究结果还表明,鼻持续气道正压通气治疗在减少白天过度困倦方面是有效的。