Vokurka E A, Thacker N A, Jackson A
Division of Imaging Science and Biomedical Engineering, Department of Medicine, University of Manchester, Manchester, England.
J Magn Reson Imaging. 1999 Oct;10(4):550-62. doi: 10.1002/(sici)1522-2586(199910)10:4<550::aid-jmri8>3.0.co;2-q.
A novel nonparametric approach for correcting intensity nonuniformity in magnetic resonance (MR) images is described. This approach is based solely on the assumption that the various sources of nonuniformity in MR imaging give rise to smooth variations in image intensity, and that these variations can be extracted and corrected for. The advantage of this computationally fast method is that it can be applied early in quantitative analysis while being independent of pulse sequence and is insensitive to pathological processes. This algorithm has been tested on both simulated and real data. Application to tissue segmentation and functional MR imaging has shown a marked improvement in quantitative analysis. J. Magn. Reson. Imaging 1999;10:550-562.
描述了一种用于校正磁共振（MR）图像强度不均匀性的新型非参数方法。该方法仅基于以下假设：MR成像中不均匀性的各种来源会导致图像强度的平滑变化，并且这些变化可以被提取并校正。这种计算速度快的方法的优点是它可以在定量分析的早期应用，同时独立于脉冲序列，并且对病理过程不敏感。该算法已在模拟数据和真实数据上进行了测试。在组织分割和功能MR成像中的应用已显示出定量分析有显著改善。《磁共振成像杂志》1999年；10：550 - 562。
