Mandishona E M, Moyo V M, Gordeuk V R, Khumalo H, Saungweme T, Gangaidzo I T, Gomo Z A, Rouault T, MacPhail A P
Department of Medicine, University of the Witwatersrand, Johannesburg, South Africa.
Eur J Clin Nutr. 1999 Sep;53(9):722-5. doi: 10.1038/sj.ejcn.1600840.
To determine if a traditional item in the diet might be useful in preventing iron deficiency in African women of child-bearing age.
In a prospective study, the iron status of women who did and did not drink traditional beer high in iron and folic acid, was compared. Iron status was determined by a combination of haemoglobin, serum ferritin and transferrin saturation.
The study was conducted amongst rural villagers in the Murehwa and Zaka districts of Zimbabwe and in Mpumalanga Province, South Africa.
112 women aged between 12 and 50 y from a population of 425 rural people participating in on-going family genetic studies.
Women who consumed traditional beer had significantly higher serum ferritin concentrations and transferrin saturations compared to non-drinkers (P = 0.0001 and 0.03 respectively). Iron deficiency anaemia was not present in drinkers but the prevalence in non-drinkers was 13%. Forty seven percent of the non-drinkers and only 14% of the drinkers had evidence of iron deficiency (P = 0.002). Six (21%) of the drinkers and none of the non-drinkers had evidence of iron overload (transferrin saturation > 55% and serum ferritin > 400 ug/l).
We conclude that the consumption of traditional beer, rich in iron, protects women against iron deficiency. While the use of an alcoholic beverage is not ideal, our findings suggest that indigenous cultural practices might be successfully employed or adapted for promoting iron nutrition.
确定一种传统饮食项目是否有助于预防非洲育龄妇女缺铁。
在一项前瞻性研究中,比较了饮用和未饮用富含铁和叶酸的传统啤酒的女性的铁状况。铁状况通过血红蛋白、血清铁蛋白和转铁蛋白饱和度综合测定。
该研究在津巴布韦穆雷瓦和扎卡区以及南非姆普马兰加省的农村村民中进行。
从参与正在进行的家庭基因研究的425名农村人口中选取了112名年龄在12至50岁之间的女性。
与不饮酒者相比,饮用传统啤酒的女性血清铁蛋白浓度和转铁蛋白饱和度显著更高(分别为P = 0.0001和0.03)。饮酒者中不存在缺铁性贫血,但不饮酒者中的患病率为13%。47%的不饮酒者和仅14%的饮酒者有缺铁迹象(P = 0.002)。6名(21%)饮酒者有铁过载迹象(转铁蛋白饱和度> 55%且血清铁蛋白> 400 μg/l),不饮酒者中则没有。
我们得出结论,饮用富含铁的传统啤酒可保护女性预防缺铁。虽然使用酒精饮料并不理想,但我们的研究结果表明,本土文化习俗可能会成功地用于促进铁营养或进行调整。