Russell R, Iribar M P, Lambson B, Brewster S, Blackwell J M, Dye C, Ajioka J W
Department of Pathology, University of Cambridge, UK.
Mol Biochem Parasitol. 1999 Sep 20;103(1):71-7. doi: 10.1016/s0166-6851(99)00117-6.
Leishmania species of the subgenus Viannia are responsible for a large proportion of New World leishmaniasis. Here we report the development of a set of microsatellite markers which are able to discriminate between all species within the subgenus Viannia, including the closely related species pairs: Leishmania (V.) braziliensis and Leishmania (V.) peruviana; Leishmania (V.) panamensis and Leishmania (V.) guyanensis. Potential species hybrids were uncovered in the analysis. These markers are sufficiently polymorphic such that within-species epidemiological, population and genetic studies are theoretically possible for all species analyzed.
维安亚亚属的利什曼原虫物种是造成新大陆大部分利什曼病的原因。在此，我们报告了一组微卫星标记的开发情况，这些标记能够区分维安亚亚属内的所有物种，包括亲缘关系密切的物种对：巴西利什曼原虫（维安亚亚属）和秘鲁利什曼原虫（维安亚亚属）；巴拿马利什曼原虫（维安亚亚属）和圭亚那利什曼原虫（维安亚亚属）。分析中发现了潜在的物种杂交种。这些标记具有足够的多态性，以至于理论上对所有分析的物种进行种内流行病学、种群和遗传学研究都是可行的。
