Tanaka T, Naquet R
Appl Neurophysiol. 1976;39(3-4):302-5. doi: 10.1159/000102507.
Amygdaloid kindling seizures with threshold stimulation was modified by electrical stimulation of certain subcortical structures such as the VL, the CGM and the MRF. Low frequency stimulations of the VL and the CGM (10 Hz) were effective for seizure inhibition. On the contrary, high frequency stimulation of the MRF (300 Hz) tended to facilitate the generalization of the seizure.
通过对某些皮层下结构(如腹外侧核、中央中核和中脑网状结构)进行电刺激,可改变杏仁核点燃阈值刺激诱发的癫痫发作。对腹外侧核和中央中核进行低频刺激(10赫兹)可有效抑制癫痫发作。相反,对中脑网状结构进行高频刺激(300赫兹)往往会促进癫痫发作的泛化。