Gupta R, Yoxall C W, Subhedar N, Shaw N J
Neonatal Intensive Care Unit, Liverpool Women's Hospital, Liverpool L8 7SS.
Arch Dis Child Fetal Neonatal Ed. 1999 Nov;81(3):F194-6. doi: 10.1136/fn.81.3.f194.
To determine whether individualised limits for arterial oxyhaemaglobin saturation by pulse oximetry (SpO(2)) are more effective for detecting hypoxia and hyperoxia in sick newborn infants than setting fixed limits.
Six hundred and ninety two simultaneous measurements of SpO(2) and partial pressure of oxygen in arterial blood (PaO(2)) were made in 95 infants. The sensitivity and specificity for predicting hypoxia and hyperoxia using various fixed SpO(2) limits and also individualised SpO(2) limits, calculated using a standard equation, were determined and compared.
None of the fixed limits for SpO(2) was both sensitive and specific for predicting hypoxia and/or hyperoxia. There was no difference between these and individualised limits.
Individualised SpO(2) limits are no more effective than fixed SpO(2) limits for predicting hypoxia and/or hyperoxia in sick newborn infants. SpO(2) monitoring is not an ideal method for assessing PaO(2).
确定通过脉搏血氧饱和度仪(SpO₂)设定个体化的动脉血氧血红蛋白饱和度限值,对于检测患病新生儿的低氧血症和高氧血症是否比设定固定限值更有效。
对95例婴儿同时进行692次SpO₂和动脉血氧分压(PaO₂)测量。确定并比较使用各种固定SpO₂限值以及使用标准方程计算的个体化SpO₂限值来预测低氧血症和高氧血症的敏感性和特异性。
SpO₂的固定限值对于预测低氧血症和/或高氧血症均不具有敏感性和特异性。这些固定限值与个体化限值之间没有差异。
对于预测患病新生儿的低氧血症和/或高氧血症,个体化SpO₂限值并不比固定SpO₂限值更有效。SpO₂监测不是评估PaO₂的理想方法。