目前目标饱和度下孕周小于29周婴儿的动脉血氧分压（Pao2）值。
Arterial oxygen tension (Pao2) values in infants <29 weeks of gestation at currently targeted saturations.
作者信息
Quine D, Stenson B J
机构信息
Neonatal Unit, Simpson Centre for Reproductive Health, Royal Infirmary of Edinburgh, Edinburgh, Scotland, UK.
出版信息
Arch Dis Child Fetal Neonatal Ed. 2009 Jan;94(1):F51-3. doi: 10.1136/adc.2007.135285. Epub 2008 Feb 19.
BACKGROUND
Oxygen saturation (Spo(2)) monitors are commonly used to determine the need for supplemental oxygen. We aimed to describe the range of arterial oxygen tensions (Pao(2)) observed in preterm infants at saturation levels targeted in current trials.
METHODS
In a cohort of 98 consecutive infants born at <29 weeks' gestation, the Pao(2) from each arterial blood gas result during the first week of life (n = 2076) was matched to the Spo(2) at time of sampling. The mean (95% CI) Pao(2) was calculated for each saturation.
RESULTS
The 95% CI of Pao(2) for the Spo(2) range 85-95% was 3.8 to 8.9 kPa. The mean (95% CI) Pao(2) at a saturation of 85% was 5.3 (3.8 to 6.8) kPa and at a saturation of 95% it was 7.2 (5.5 to 8.9) kPa.
CONCLUSION
Saturations within the range 85-95% largely exclude hyperoxia in preterm infants <29 weeks' gestation but permit Pao(2) values far lower than those recommended in traditional guidelines.
背景
氧饱和度（Spo₂）监测仪常用于确定是否需要补充氧气。我们旨在描述当前试验中针对的饱和度水平下早产儿的动脉血氧分压（Pao₂）范围。
方法
在一组98例孕周小于29周的连续出生婴儿中，将出生后第一周内每次动脉血气结果中的Pao₂（n = 2076）与采样时的Spo₂进行匹配。计算每个饱和度下的平均（95%CI）Pao₂。
结果
Spo₂范围为85 - 95%时，Pao₂的95%CI为3.8至8.9 kPa。饱和度为85%时，平均（95%CI）Pao₂为5.3（3.8至6.8）kPa；饱和度为95%时，平均（95%CI）Pao₂为7.2（5.5至8.9）kPa。
结论
85 - 95%范围内的饱和度在很大程度上可排除孕周小于29周早产儿的高氧情况，但允许Pao₂值远低于传统指南中推荐的值。
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