Malinina L V, Kosaganov Iu N, Lazurkin Iu S
Mol Biol (Mosk). 1976 Nov-Dec;10(6):1349-54.
It has been shown that formaldehyde has no marked physical effect upon DNA resulting in lowering of its melting temperature. The effect of lowering of DNA melting temperature observed earlier by other authors resulted from the process of unwinding of DNA due to chemical reactions of formaldehyde with reactive base groups.