[甲醛对DNA解链温度的影响]
[Influence of formaldehyde on the melting temperature of DNA].
作者信息
Malinina L V, Kosaganov Iu N, Lazurkin Iu S
出版信息
Mol Biol (Mosk). 1976 Nov-Dec;10(6):1349-54.
PMID:1053262
Abstract
It has been shown that formaldehyde has no marked physical effect upon DNA resulting in lowering of its melting temperature. The effect of lowering of DNA melting temperature observed earlier by other authors resulted from the process of unwinding of DNA due to chemical reactions of formaldehyde with reactive base groups.
摘要
业已表明，甲醛对DNA没有显著的物理作用，不会导致其解链温度降低。其他作者先前观察到的DNA解链温度降低的效应，是由于甲醛与活性碱基基团发生化学反应，导致DNA解旋过程所致。
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