Dasan S, Neill S M, Donaldson D R, Scott H J
Departments of Colorectal Surgery and Dermatology, St Peter's Hospital, Ashford, UK.
Br J Surg. 1999 Oct;86(10):1337-40. doi: 10.1046/j.1365-2168.1999.01231.x.
Pruritus ani is a common and socially embarrassing condition which is often poorly managed. It is often classified as idiopathic where the symptoms are usually transitory or secondary when a more persistent itch is experienced. The aim of this study was to establish the cause of pruritus ani in a group of patients referred to a combined colorectal and dermatological clinic, and to determine the most appropriate treatment.
Forty consecutive patients with pruritus ani were referred over a 6-month period from either the general practitioner or another hospital consultant to a combined colorectal and dermatological clinic. They were assessed by history, completion of a general health questionnaire, full examination of the skin, digital rectal examination, proctoscopy, sigmoidoscopy and patch testing. Patients were treated according to clinical findings at assessment.
Thirty-four patients had a recognizable dermatosis, three had superficial perianal fissuring and three had a normal perineum; two required surgical intervention. Eighteen patients had a positive reaction when patch tested. All patients have shown an improvement or complete resolution of symptoms with treatment.
This series has shown that the majority of patients presenting with pruritus ani have a dermatosis as the underlying cause of their symptoms and that many of them have developed contact sensitivities to the various topical medications used. These findings suggest that referral to a dermatologist in the first instance may be more appropriate.
肛门瘙痒是一种常见且令人尴尬的病症,其治疗往往效果不佳。通常分为特发性,症状多为短暂性;或继发性,即出现更持续的瘙痒。本研究旨在确定转诊至结直肠与皮肤科联合门诊的一组患者肛门瘙痒的病因,并确定最合适的治疗方法。
在6个月期间,连续40例肛门瘙痒患者从全科医生或其他医院顾问处转诊至结直肠与皮肤科联合门诊。通过病史、填写一般健康问卷、全面皮肤检查、直肠指检、直肠镜检查、乙状结肠镜检查和斑贴试验对患者进行评估。根据评估时的临床发现对患者进行治疗。
34例患者有可识别的皮肤病,3例有浅表性肛周裂伤,3例会阴正常;2例需要手术干预。18例患者斑贴试验呈阳性反应。所有患者经治疗后症状均有改善或完全缓解。
该系列研究表明,大多数肛门瘙痒患者的潜在病因是皮肤病,其中许多人对所使用的各种局部用药产生了接触性敏感。这些发现表明,首先转诊至皮肤科医生处可能更为合适。