吉米沙星（SB 265805，LB20304）对近期肺炎衣原体临床分离株的体外活性。
In vitro activities of gemifloxacin (SB 265805, LB20304) against recent clinical isolates of Chlamydia pneumoniae.
作者信息
Roblin P M, Reznik T, Kutlin A, Hammerschlag M R
机构信息
Division of Infectious Diseases, Department of Pediatrics, Health Science Center at Brooklyn, State University of New York, Brooklyn, New York 11203, USA.
出版信息
Antimicrob Agents Chemother. 1999 Nov;43(11):2806-7. doi: 10.1128/AAC.43.11.2806.
Abstract
We compared the in vitro activity of gemifloxacin, a new quinolone antibiotic, to the activities of levofloxacin, moxifloxacin, trovafloxacin, erythromycin, and doxycycline against 20 isolates of Chlamydia pneumoniae. Gemifloxacin was the most active quinolone tested, with a MIC at which 90% of the isolates are inhibited and a minimal bactericidal concentration at which 90% of strains tested are killed of 0.25 microg/ml, but this activity was less than those of doxycycline and erythromycin.
摘要
我们比较了新型喹诺酮类抗生素吉米沙星与左氧氟沙星、莫西沙星、曲伐沙星、红霉素和强力霉素对20株肺炎衣原体的体外活性。吉米沙星是所测试的喹诺酮类药物中活性最强的，其90%分离株被抑制时的最低抑菌浓度（MIC）以及90%测试菌株被杀死时的最低杀菌浓度为0.25微克/毫升，但其活性低于强力霉素和红霉素。
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