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J Hyg (Lond). 1975 Apr;74(2):261-70. doi: 10.1017/s0022172400024335.
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本文引用的文献

1
The antistreptococcal property of milk. I. Some characteristics of the activity of lactenin in vitro; the effect of lactenin on hemolytic streptococci of the several serological groups.牛奶的抗链球菌特性。一、乳抑菌素体外活性的一些特征；乳抑菌素对几个血清学组溶血性链球菌的影响。
J Exp Med. 1952 Jan;95(1):25-38. doi: 10.1084/jem.95.1.25.
2
Inhibition of growth of pleuropneumonia-like organisms by antibody.抗体对类胸膜肺炎微生物生长的抑制作用。
J Pathol Bacteriol. 1954 Jul;68(1):23-30. doi: 10.1002/path.1700680104.
3
Studies of the microbiology and pathology of pneumonic lungs of calves.犊牛肺炎性肺脏的微生物学与病理学研究。
J Comp Pathol. 1970 Oct;80(4):575-84. doi: 10.1016/0021-9975(70)90055-1.
4
A new mycoplasma species isolated from pneumonic lungs of calves (Mycoplasma dispar sp. nov.).从患肺炎的犊牛肺中分离出的一种新支原体物种（新种支原体 dispar）。
J Med Microbiol. 1970 Feb;3(1):111-23. doi: 10.1099/00222615-3-1-111.
5
The isolation of T-mycoplasmas from the urogenital tract of bulls.从公牛泌尿生殖道分离出T支原体。
J Med Microbiol. 1969 Nov 4;2(4):527-33. doi: 10.1099/00222615-2-4-527.
6
A molecular concept of immune cytolysis.免疫细胞溶解的分子概念。
Arch Pathol. 1966 Sep;82(3):205-17.
7
Interaction of porcine mycoplasmas with fresh animal serum.猪支原体与新鲜动物血清的相互作用。
J Hyg (Lond). 1971 Sep;69(3):361-8. doi: 10.1017/s0022172400021604.
8
Antimicrobial proteins isolated from the teat canal of the cow.从奶牛乳头管中分离出的抗菌蛋白。
J Gen Microbiol. 1969 Jun;56(3):365-71. doi: 10.1099/00221287-56-3-365.
9
Inhibition of bacteria by lactoferrin and other iron-chelating agents.乳铁蛋白及其他铁螯合剂对细菌的抑制作用。
Biochim Biophys Acta. 1968 Dec 23;170(2):351-65. doi: 10.1016/0304-4165(68)90015-9.
10
Enhanced isolation of Mycoplasma dispar by substitution of ampicillin for benzylpenicillin in growth media.通过在生长培养基中用氨苄青霉素替代苄青霉素来增强马鼻支原体的分离。
Vet Rec. 1973 Dec 8;93(23):603. doi: 10.1136/vr.93.23.603-a.

正常牛乳清中存在一种可透析成分，能够杀死多种牛支原体。

Presence of a dialysable fraction in normal bovine whey capable of killing several species of bovine mycoplasmas.

作者信息

Howard C J, Brownlie J, Gourlay R N, Collins J

出版信息

J Hyg (Lond). 1975 Apr;74(2):261-70. doi: 10.1017/s0022172400024335.

DOI:10.1017/s0022172400024335
PMID:1054730
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2130383/
Abstract

Most normal bovine whey samples contain a fraction that survives heating at 56 degrees C. for 30 min., passes through a dialysis membrane and kills a maximum of seven out of ten of the different bovine mycoplasma species tested. Some whey samples appear more active than other but not all affect the same strains of mycoplasma indicating some specificity in their action. Absorption of the active factor from whey by heterologous and homologous mycoplasmas and by erythrocytes was observed. Binding of the factor to mycoplasmas appears to be temperature-dependent and non-specific, but subsequent mycoplasmacidal action shows some specificity.

摘要

大多数正常牛乳清样品含有一种在56摄氏度下加热30分钟后仍能存活的成分，该成分能透过透析膜，并能杀死所测试的十种不同牛支原体中的最多七种。一些乳清样品似乎比其他样品更具活性，但并非所有样品都对相同的支原体菌株有影响，这表明它们的作用具有一定的特异性。观察到活性因子可被异源和同源支原体以及红细胞从乳清中吸收。该因子与支原体的结合似乎与温度有关且是非特异性的，但随后的杀支原体作用显示出一定的特异性。