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拔牙窝封闭手术中自体咀嚼黏膜移植:脱矿冻干骨与脱蛋白牛骨矿物质移植拔牙窝的比较

Autogenous masticatory mucosal grafts in extraction socket seal procedures: a comparison between sockets grafted with demineralized freeze-dried bone and deproteinized bovine bone mineral.

作者信息

Tal H

机构信息

Department of Periodontology, Maurice and Gabriela Goldschleger School of Dental Medicine, Tel Aviv University, Israel.

出版信息

Clin Oral Implants Res. 1999 Aug;10(4):289-96. doi: 10.1034/j.1600-0501.1999.100405.x.

DOI:10.1034/j.1600-0501.1999.100405.x
PMID:10551071
Abstract

Successful preservation of the edentulous ridge after extractions may eliminate or reduce the need for ridge augmentation procedures. It has been claimed that grafting fresh extraction sockets and sealing them with autogenous soft tissue grafts promote ridge preservation after tooth extraction. In this study, the survival of free autogenous connective tissue grafts sealing extraction sites was evaluated. In 24 healthy patients, 42 maxillary anterior teeth were extracted. After socket debridement, soft tissue margins of the socket orifice were carefully cut to remove epithelial debris, Sockets were filled with either demineralized freeze-dried bone allografts (DFDBA) or deproteinized natural bovine bone mineral xenograft (DBBMX) to the level of the alveolar bone crest. Circular connective tissue grafts, slightly larger in diameter than the soft tissue socket orifice, were obtained and placed on top of the filler graft material sealing the sockets. Grafts were stabilized and secured by sutures and inspected weekly for the first month. The grafts were classified into 3 groups according to clinical parameters: vital, partially vital and non-vital. After 1 week, 18 grafts were vital, 13 partially vital and 11 non-vital. When only 1 sample unit (1 site per patient) was compared between DFDBA and DBBMX grafted sockets, no significant difference in graft vitality was shown (P = 0.34 for vital; P = 0.67 for vital plus partially vital). After 1 month, all socket orifices were sealed with mucosa. Based on the present observations, it seems that connective tissue grafts sealing fresh extraction sites are mainly dependent on underlying tissue vascularization and that sealing grafted fresh extraction sockets filled with bone substitute allograft or xenograft materials may be beneficial but an unpredictable procedure.

摘要

拔牙后成功保留无牙颌骨嵴可消除或减少骨增量手术的需求。据称,用自体软组织移植物移植新鲜拔牙窝并密封可促进拔牙后骨嵴的保留。在本研究中,评估了密封拔牙部位的游离自体结缔组织移植物的存活情况。24例健康患者拔除了42颗上颌前牙。拔牙窝清创后,仔细切除拔牙窝口的软组织边缘以去除上皮碎屑,拔牙窝用脱矿冻干骨同种异体移植物(DFDBA)或脱蛋白天然牛骨矿物质异种移植物(DBBMX)填充至牙槽嵴水平。获取直径略大于软组织拔牙窝口的圆形结缔组织移植物,并放置在填充移植物材料上方以密封拔牙窝。移植物通过缝线固定并每周检查一次,持续第一个月。根据临床参数将移植物分为3组:存活、部分存活和无活力。1周后,18个移植物存活,13个部分存活,11个无活力。当仅比较DFDBA和DBBMX移植拔牙窝之间的1个样本单位(每位患者1个部位)时,移植物活力无显著差异(存活:P = 0.34;存活加部分存活:P = 0.67)。1个月后,所有拔牙窝口均被黏膜封闭。基于目前的观察结果,似乎密封新鲜拔牙部位的结缔组织移植物主要依赖于下方组织的血管化,并且用骨替代同种异体移植物或异种移植物材料密封移植的新鲜拔牙窝可能是有益的,但却是一个不可预测的过程。

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