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引导骨组织再生术联合或不联合纤维蛋白胶在牙槽嵴保存中的随机对照研究:软组织和硬组织变化的临床研究。

Alveolar Ridge Preservation With Fibro-Gide or Connective Tissue Graft: A Randomized Controlled Trial of Soft and Hard Tissue Changes.

机构信息

Department of Periodontology, Faculty of Dental Medicine, Damascus University, Damascus, Syria.

出版信息

Clin Exp Dent Res. 2024 Aug;10(4):e929. doi: 10.1002/cre2.929.

Abstract

OBJECTIVE

The aim of this study was to evaluate the effectiveness of a novel biomaterial (FG) for alveolar ridge preservation compared to CTG in terms of soft tissue thickness and bone dimensional changes.

MATERIALS AND METHODS

A randomized clinical trial was conducted on 30 patients who required extraction of 30 hopeless mandibular posterior teeth. All patients went through atraumatic tooth extraction, and then, they were randomly allocated to either a CTG, an FG, or a spontaneous healing (SH) group (1:1:1). All patients received a dental implant placed 6 months postoperatively. The soft tissue thickness and bone dimensional changes were measured before and 6 months after the procedure.

RESULTS

The study's analysis revealed statistically significant differences in buccal gingival thickness and dimensional bone changes across the three examined groups after 6 months (p < 0.05). The SH group had lower gingival thickness (1.31 ± 0.65 mm) and higher vertical resorption (-1.46 ± 1.67 mm at the buccal aspect) compared with the CTG and FG groups. The CTG and FG groups had similar gingival thickness (2.42 ± 0.70 and 3.00 ± 0.71 mm, respectively) and bone width reduction (+0.86 ± 2.31 and +0.93 ± 2.38 mm, respectively), whereas the CTG group had lower vertical bone loss (-0.30 ± 1.09 mm at the buccal aspect) than the FG group (-0.47 ± 2.30 mm at the buccal aspect).

CONCLUSION

FG and CTG demonstrate equivalent soft tissue thickness and comparable horizontal bone dimension outcomes in ARP.

摘要

目的

本研究旨在评估一种新型生物材料(FG)在牙槽嵴保存方面的效果,与 CTG 相比,从软组织厚度和骨量变化方面进行评估。

材料与方法

对 30 名需拔除 30 颗下颌后牙的患者进行了一项随机临床试验。所有患者均行微创拔牙,随后随机分为 CTG 组、FG 组或自然愈合(SH)组(1:1:1)。所有患者均在术后 6 个月接受牙种植体植入。在术前和术后 6 个月时测量软组织厚度和骨量变化。

结果

研究分析显示,术后 6 个月时,三组的颊侧龈厚度和骨量变化存在统计学差异(p<0.05)。SH 组的龈厚度(1.31±0.65mm)较低,颊侧垂直吸收量(-1.46±1.67mm)较高,与 CTG 组和 FG 组相比。CTG 组和 FG 组的龈厚度相似(分别为 2.42±0.70mm 和 3.00±0.71mm),骨宽度减少量也相似(分别为+0.86±2.31mm 和+0.93±2.38mm),但 CTG 组颊侧的垂直骨丢失量(-0.30±1.09mm)低于 FG 组(-0.47±2.30mm)。

结论

FG 和 CTG 在 ARP 中均表现出相似的软组织厚度和相似的水平骨量结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f4a/11263734/0fd54b664049/CRE2-10-e929-g006.jpg

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