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一名川崎病患者发生致命性心脏压塞。

Fatal cardiac tamponade in a patient with Kawasaki disease.

作者信息

Ozdogu Hakan, Boga Can

机构信息

Department of Internal Medicine, Baskent University Faculty of Medicine, Adana Teaching and Medical Research Center, Adana, Turkey.

出版信息

Heart Lung. 2005 Jul-Aug;34(4):257-9. doi: 10.1016/j.hrtlng.2004.12.003.

DOI:10.1016/j.hrtlng.2004.12.003
PMID:16027646
Abstract

Kawasaki disease (KD) is usually a self-limiting condition, but cardiac complications are not uncommon and can lead to significant morbidity and mortality. This article describes the case of an 18-year-old man with rapidly progressive and ultimately fatal KD. Polyserositis syndrome and cardiac tamponade developed during a convalescent phase of the illness. Treatment with high-dose corticosteroid and intravenous immunoglobulin-G therapy was unsuccessful. The patient continued to deteriorate despite supportive care. Severe cardiac tamponade developed, and percutaneous pericardiocentesis was performed, but the patient died hours later. This is the second reported case of KD featuring a polyserositis syndrome and impending cardiac tamponade, and the first with fatal outcome.

摘要

川崎病(KD)通常是一种自限性疾病,但心脏并发症并不罕见,可导致严重的发病和死亡。本文描述了一名18岁男性患快速进展且最终致命的川崎病的病例。在疾病的恢复期出现了多浆膜炎综合征和心脏压塞。高剂量皮质类固醇和静脉注射免疫球蛋白-G治疗均未成功。尽管给予了支持性治疗,患者仍持续恶化。出现了严重的心脏压塞,进行了经皮心包穿刺术,但患者数小时后死亡。这是第二例报道的以多浆膜炎综合征和即将发生的心脏压塞为特征的川崎病病例,也是首例出现致命结局的病例。

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引用本文的文献

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Autoptic Findings in Cases of Sudden Death Due to Kawasaki Disease.川崎病所致猝死病例的尸体解剖结果
Diagnostics (Basel). 2023 May 23;13(11):1831. doi: 10.3390/diagnostics13111831.
2
Cardiovascular Involvement in Kawasaki Disease Is Much More Than Mere Coronary Arteritis.川崎病中的心血管受累远不止单纯的冠状动脉炎。
Front Pediatr. 2020 Sep 24;8:526969. doi: 10.3389/fped.2020.526969. eCollection 2020.
3
Perioperative considerations of kawasaki disease.川崎病的围手术期注意事项
Ochsner J. 2013 Summer;13(2):208-13.
4
Evidence for the use of intravenous immunoglobulins--a review of the literature.静脉注射免疫球蛋白的应用证据——文献综述。
Clin Rev Allergy Immunol. 2010 Apr;38(2-3):201-69. doi: 10.1007/s12016-009-8155-9.