Pilania Rakesh Kumar, Jindal Ankur Kumar, Bhattarai Dharmagat, Naganur Sanjeev Hanumantacharya, Singh Surjit
Allergy Immunology Unit, Department of Paediatrics, Advances Paediatrics Centre, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Department of Cardiology, Advances Cardiac Centre, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Front Pediatr. 2020 Sep 24;8:526969. doi: 10.3389/fped.2020.526969. eCollection 2020.
Kawasaki disease (KD) is now a common cause of acquired heart disease in children. Coronary artery involvement is the most serious complication in children with KD. Several non-coronary complications have now been identified in this condition but these are often overlooked. Myocarditis is an integral component of KD and may be more common than coronary artery abnormalities. Pericardial involvement and valvular abnormalities have also been observed in patients with KD. KD shock syndrome is now being increasingly recognized and may be difficult to differentiate clinically from toxic shock syndrome. Endothelial dysfunction has been reported both during acute stage and also on follow-up. This may be a potentially modifiable cardiovascular risk factor.
川崎病（KD）现已成为儿童后天性心脏病的常见病因。冠状动脉受累是KD患儿最严重的并发症。目前已在这种疾病中发现了几种非冠状动脉并发症，但这些并发症常常被忽视。心肌炎是KD的一个重要组成部分，可能比冠状动脉异常更为常见。KD患者还观察到心包受累和瓣膜异常。KD休克综合征现在越来越受到认可，临床上可能难以与中毒性休克综合征相鉴别。在急性期及随访期间均有内皮功能障碍的报道。这可能是一个潜在的可改变的心血管危险因素。
