Schuchert A, Meinertz T
Medizinische Klinik, Abteilung für Kardiologie, Universitäts-Krankenhaus Eppendorf, Martinistr. 52, D-20246 Hamburg.
Z Kardiol. 1999 Oct;88(10):823-7. doi: 10.1007/s003920050358.
The aim of the study was to compare the clinical outcome after AV node radiofrequency current ablation and pacemaker implantation in patients with permanent and paroxysmal atrial fibrillation. The study consecutively included 19 patients with permanent (male n = 15; 55 +/- 13 years) and 45 patients with paroxysmal atrial fibrillation (male n = 31; 60 +/- 13 years). Clinical evaluation before and 1 year after ablation included the symptoms and the self-assessed state of health. Before ablation, both groups reported with a similar frequency about tachycardia (permanent n = 15; paroxysmal n = 2) and palpitations (permanent n = 5; paroxysmal n = 19). Patients with permanent (n = 7) atrial fibrillation had more often breathlessness than patients with paroxysmal atrial fibrillation (n = 2), whereas dizziness/syncope was more often reported by patients with paroxysmal (n = 35) than with permanent arrhythmia (n = 8). Ablation improved symptoms in patients with permanent (89%) as well as with paroxysmal atrial fibrillation (84%). The self-assessed state of health described as good had not patient before ablation and 63% patients with permanent and 47% with paroxysmal atrial fibrillation after ablation. There were no differences for the studied parameters between patients with permanent and paroxysmal atrial fibrillation.
AV node ablation and pacemaker implantation improved the symptoms and the state of health in with paroxysmal and paroxysmal atrial fibrillation. No differences were detected between patients with permanent and paroxysmal atrial fibrillation.
本研究的目的是比较永久性和阵发性心房颤动患者在房室结射频电流消融和起搏器植入后的临床结果。该研究连续纳入了19例永久性心房颤动患者(男性15例;年龄55±13岁)和45例阵发性心房颤动患者(男性31例;年龄60±13岁)。消融术前和术后1年的临床评估包括症状和自我评估的健康状况。消融术前,两组报告心动过速(永久性组15例;阵发性组2例)和心悸(永久性组5例;阵发性组19例)的频率相似。永久性心房颤动患者(7例)比阵发性心房颤动患者(2例)更常出现呼吸急促,而阵发性心房颤动患者(35例)比永久性心律失常患者(8例)更常报告头晕/晕厥。消融改善了永久性心房颤动患者(89%)以及阵发性心房颤动患者(84%)的症状。消融术前没有患者将自我评估健康状况描述为良好,消融术后永久性心房颤动患者中有63%、阵发性心房颤动患者中有47%将自我评估健康状况描述为良好。永久性和阵发性心房颤动患者在研究参数方面没有差异。
房室结消融和起搏器植入改善了阵发性和永久性心房颤动患者症状和健康状况。永久性和阵发性心房颤动患者之间未检测到差异。