Jensen S M, Bergfeldt L, Rosenqvist M
Department of Medicine, University Hospital, Umeå, Sweden.
Pacing Clin Electrophysiol. 1995 Sep;18(9 Pt 1):1609-14. doi: 10.1111/j.1540-8159.1995.tb06982.x.
Radiofrequency ablation of the AV conduction tissue (His-bundle ablation) is an accepted treatment for therapy resistant atrial fibrillation/flutter. However, data on the long-term effects of the procedure are limited. We followed 50 patients for a mean of 17 months after AV junction ablation. The indication was treatment resistant atrial fibrillation or flutter. The patients underwent a standardized interview performed by two nurses. Health care was studied via the in-patient register. Subjective improvement was reported by 88% and the number of days in hospital per year was reduced from 17 to 7. The use of antiarrhythmic drugs was reduced by 75%. If the reduction in costs of drugs and days in hospital is compared with the cost of the ablation and the pacemaker implantation, breaking even is achieved after 2.6 years. We could not confirm that patients with paroxysmal atrial fibrillation note less improvement than those with chronic fibrillation.
Ablation of the AV junction is a cost effective treatment with good long-term results and relatively few complications.
Chronic atrial fibrillation: If sinus rhythm cannot be established and in cases in which heart rate regulating drugs have been ineffective, ablation of the AV junction with implantation of a VVIR pacemaker is recommended.
If the patient despite treatment with antiarrhythmic drugs continues to have symptomatic episodes of atrial fibrillation, then AV junction ablation with implantation of a permanent pacemaker is recommended. Patients who have self-limiting episodes of atrial fibrillation should be given a DDDR pacemaker with an automatic mode switch. Patients who do not have self-limiting attacks and require DC conversion, should receive a VVIR pacemaker.
房室传导组织的射频消融术(希氏束消融术)是治疗难治性心房颤动/扑动的一种公认疗法。然而,该手术长期效果的数据有限。我们对50例患者在房室结消融术后平均随访了17个月。适应证为难治性心房颤动或扑动。患者接受了由两名护士进行的标准化访谈。通过住院登记研究医疗保健情况。88%的患者报告主观症状改善,每年住院天数从17天减少到7天。抗心律失常药物的使用减少了75%。如果将药物费用和住院天数的减少与消融术及起搏器植入的费用进行比较,2.6年后实现收支平衡。我们无法证实阵发性心房颤动患者的改善程度不如慢性心房颤动患者。
房室结消融术是一种具有成本效益的治疗方法,长期效果良好且并发症相对较少。
慢性心房颤动:如果无法建立窦性心律且心率调节药物无效,建议进行房室结消融并植入VVIR起搏器。
如果患者尽管使用抗心律失常药物治疗仍持续出现有症状的心房颤动发作,则建议进行房室结消融并植入永久性起搏器。心房颤动发作具有自限性的患者应给予具有自动模式转换功能的DDDR起搏器。无自限性发作且需要直流电复律的患者应接受VVIR起搏器。