沿基因频率变化的随机路径上基因频率的任意函数之和的矩。
Moments for sum of an arbitrary function of gene frequency along a stochastic path of gene frequency change.
作者信息
Maruyama T, Kimura M
出版信息
Proc Natl Acad Sci U S A. 1975 Apr;72(4):1602-4. doi: 10.1073/pnas.72.4.1602.
Abstract
A diffusion model is developed to compute any moment of the sum of an arbitrary function of the gene frequency along sample paths between any two specified frequencies. This is used to calculate the mean age of a mutant of frequency chi, including or excluding the possibility of its having been at value chi equals 1 during the process, and the total frequency of heterozygotes involving an allele since its origin.
摘要
开发了一种扩散模型，用于计算任意两个指定频率之间样本路径上基因频率的任意函数之和的任意矩。这用于计算频率为χ的突变体的平均年龄，包括或排除其在过程中处于χ等于1的可能性，以及自等位基因起源以来涉及该等位基因的杂合子的总频率。
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