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约旦的唾液腺肿瘤:对221例患者的回顾性研究。

Salivary gland tumors in Jordan: a retrospective study of 221 patients.

作者信息

Ma'aita J K, Al-Kaisi N, Al-Tamimi S, Wraikat A

机构信息

Departments of Oral and Maxillofacial Surgery, King Hussein Medical Center, P.O. Box 563, Tariq ZC 11947, Amman, Jordan.

出版信息

Croat Med J. 1999 Dec;40(4):539-42.

Abstract

AIM

To evaluate the types and clinical outcome of salivary gland tumors in Jordan.

METHODS

Hospital records of 221 patients (85 women and 136 men) with salivary gland tumors, diagnosed from January 1988 to December 1997 were reviewed. The patients were analyzed according to sex, age, histopathological type and site of the tumor. Survival curves for patients with malignant tumors were constructed using Kaplan-Meier's method.

RESULTS

Of the total 221 salivary gland tumors, 155 (70.2%) were parotid tumors, 42 (19%) minor salivary gland tumors, 23 (10.4%) submandibular gland tumors, and a single (0.4%) sublingual gland tumor. Most of the tumors (151, or 68.4%) were classified as benign and 70 (31.6%) were malignant. Men to women ratio was 1.6:1, and the age of the patients ranged from 2 to 81 years. The overall 5 and 10 year-survival rates for the 70 malignant tumors were 67% and 53%, respectively, for all tumor stages. Mucoepidermoid carcinoma had the best, and squamous cell carcinoma the worst 10-year survival rate. Patients treated with surgery and subsequent radiation therapy had better survival rates than those treated with surgery or radiation therapy alone.

CONCLUSION

The principal site for salivary gland tumors in Jordan population was the parotid, and the pleo- morphic adenoma the most common pathological finding. Tumor characteristics and survival data for the Jordanian population are comparable to those from western countries.

摘要

目的

评估约旦涎腺肿瘤的类型及临床结局。

方法

回顾1988年1月至1997年12月确诊的221例涎腺肿瘤患者(85例女性和136例男性)的医院记录。根据患者的性别、年龄、组织病理学类型及肿瘤部位进行分析。采用Kaplan-Meier法构建恶性肿瘤患者的生存曲线。

结果

在221例涎腺肿瘤中,155例(70.2%)为腮腺肿瘤,42例(19%)为小涎腺肿瘤,23例(10.4%)为下颌下腺肿瘤,1例(0.4%)为舌下腺肿瘤。大多数肿瘤(151例,占68.4%)被分类为良性,70例(31.6%)为恶性。男女比例为1.6:1,患者年龄范围为2至81岁。70例恶性肿瘤在所有肿瘤分期中的总体5年和10年生存率分别为67%和53%。黏液表皮样癌的10年生存率最佳,鳞状细胞癌最差。接受手术及后续放疗的患者生存率高于单纯接受手术或放疗的患者。

结论

约旦人群涎腺肿瘤的主要部位是腮腺,多形性腺瘤是最常见的病理表现。约旦人群的肿瘤特征及生存数据与西方国家的相当。

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