Lindhe J, Nyman S
J Clin Periodontol. 1975 Apr;2(2):67-79. doi: 10.1111/j.1600-051x.1975.tb01727.x.
The present clinical study was initiated in 1969 to test the hypothesis that microbial plaque is the cause of periodontal disease and that hence even advanced cases of periodontitis can be cured in patients willing to exercise optimal plaque control. The material consisted of 75 patients with severe destruction of the periodontal tissues. The patients were selected for the study because of their ability to maintain plaque-free dentition. Following an initial examination, a preliminary treatment plan was presented to the patients. This plan included detailed instructions in plaque control measures, scaling, root planning and emergency dental care, including endodontic therapy and extractions. Three to six months after the termination of the so-called presurgical treatment, surgical elimination of pathologically deepened pockets was performed. The patients were recalled every 3 to 6 months after the end of the treatment. At these reexaminations the following parameters were assessed: Plaque Index, Gingival Index, Pocket Depths, Marginal alveolar bone topography and height. The results demonstrate that it is possible to treat periodontal disease successfully, even in advanced stages, in patients willing to maintain plaque-free dentition.
本临床研究始于1969年,旨在验证以下假设:微生物菌斑是牙周病的病因,因此,对于愿意进行最佳菌斑控制的患者,即使是晚期牙周炎病例也可治愈。研究对象为75例牙周组织严重破坏的患者。选择这些患者进行研究是因为他们有能力保持牙列无菌斑。在初步检查后,向患者提出了初步治疗方案。该方案包括菌斑控制措施、龈上洁治、根面平整和应急牙科护理(包括牙髓治疗和拔牙)的详细指导。在所谓的术前治疗结束后三至六个月,对病理性加深的牙周袋进行手术消除。治疗结束后,每3至6个月召回患者一次。在这些复查中,评估了以下参数:菌斑指数、牙龈指数、牙周袋深度、牙槽嵴顶形态和高度。结果表明,对于愿意保持牙列无菌斑的患者,即使在晚期,也有可能成功治疗牙周病。