西尼罗病毒样病毒性脑炎暴发——纽约，1999年

Outbreak of West Nile-like viral encephalitis--New York, 1999.

出版信息

MMWR Morb Mortal Wkly Rep. 1999 Oct 1;48(38):845-9.

Abstract

An outbreak of arboviral encephalitis was first recognized in New York City in late August and has since been identified in neighboring counties in New York state. Although initially attributed to St. Louis encephalitis (SLE) virus based on positive serologic findings in cerebrospinal fluid (CSF) and serum samples using a virus-specific IgM-capture enzyme-linked immunosorbent assay (ELISA), the cause of the outbreak has been confirmed as a West Nile-like virus based on the identification of virus in human, avian, and mosquito samples.

摘要

8月下旬，纽约市首次发现虫媒病毒性脑炎疫情，此后纽约州的邻近县也发现了该疫情。尽管最初根据脑脊液（CSF）和血清样本中使用病毒特异性IgM捕获酶联免疫吸附测定（ELISA）的阳性血清学结果，将疫情归因于圣路易斯脑炎（SLE）病毒，但根据在人类、禽类和蚊子样本中发现病毒，已确认此次疫情的病因是一种西尼罗样病毒。