White O, Eisen J A, Heidelberg J F, Hickey E K, Peterson J D, Dodson R J, Haft D H, Gwinn M L, Nelson W C, Richardson D L, Moffat K S, Qin H, Jiang L, Pamphile W, Crosby M, Shen M, Vamathevan J J, Lam P, McDonald L, Utterback T, Zalewski C, Makarova K S, Aravind L, Daly M J, Minton K W, Fleischmann R D, Ketchum K A, Nelson K E, Salzberg S, Smith H O, Venter J C, Fraser C M
Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA.
Science. 1999 Nov 19;286(5444):1571-7. doi: 10.1126/science.286.5444.1571.
The complete genome sequence of the radiation-resistant bacterium Deinococcus radiodurans R1 is composed of two chromosomes (2,648,638 and 412,348 base pairs), a megaplasmid (177,466 base pairs), and a small plasmid (45,704 base pairs), yielding a total genome of 3,284, 156 base pairs. Multiple components distributed on the chromosomes and megaplasmid that contribute to the ability of D. radiodurans to survive under conditions of starvation, oxidative stress, and high amounts of DNA damage were identified. Deinococcus radiodurans represents an organism in which all systems for DNA repair, DNA damage export, desiccation and starvation recovery, and genetic redundancy are present in one cell.
抗辐射细菌耐辐射球菌R1的完整基因组序列由两条染色体（2,648,638和412,348个碱基对）、一个大质粒（177,466个碱基对）和一个小质粒（45,704个碱基对）组成，基因组总长为3,284,156个碱基对。已鉴定出分布在染色体和大质粒上的多个组成部分，这些组成部分有助于耐辐射球菌在饥饿、氧化应激和大量DNA损伤条件下存活。耐辐射球菌代表了一种在单个细胞中具备所有DNA修复、DNA损伤输出、干燥和饥饿恢复以及遗传冗余系统的生物体。
