Perron Lepage M F, Gerber V, Suter M M
Département Hippique, Ecole Nationale Vétérinaire de Lyon, Marcy l'Etoile, France.
Vet Pathol. 1999 Nov;36(6):621-4. doi: 10.1354/vp.36-6-621.
Subacute interstitial pneumonia with diffuse alveolar damage, marked macrophage infiltration, and intracellular Pneumocystis carinii cysts is described in a 3-month-old Swiss warmblood foal. Clinically, the disease was characterized by sudden onset of respiratory distress with fatal outcome. Based on serum immunoglobulin G (IgG), IgA, and IgM values, no humoral immunosuppression was detected. Spleen, thymus, and bronchial lymph nodes did not reveal lymphoid depletion, as assessed by immunohistochemical staining of CD-3-positive cells. Immunopathogenesis of pulmonary infections with intracellular agents in foals is discussed.
