Ariffin H, Ariffin W, Tharam S, Omar A, de Bruyne J, Lin H P
Department of Paediatrics, University Malaya Medical Centre, Kuala Lumpur, Malaysia.
Singapore Med J. 1999 Aug;40(8):533-6.
Candida species is now being increasingly recognised as an important cause of endocarditis especially in immunocompromised patients. A case of Candida albicans endocarditis in a child with acute lymphoblastic leukemia (ALL) is reported. The child did not have a central venous catheter at any time. Treatment consisted of intravenous amphotericin B and fluconazole for 3 weeks followed by oral fluconazole for 2 weeks. No surgical resection was necessary. We highlight here the importance of echocardiography in the management of prolonged febrile neutropenia and discuss the dilemma of continuing chemotherapy in such patients.
念珠菌属如今越来越被认为是心内膜炎的重要病因,尤其是在免疫功能低下的患者中。本文报告了一例急性淋巴细胞白血病(ALL)患儿发生白色念珠菌心内膜炎的病例。该患儿在任何时候都没有中心静脉导管。治疗包括静脉注射两性霉素B和氟康唑3周,随后口服氟康唑2周。无需进行手术切除。我们在此强调超声心动图在长期发热性中性粒细胞减少症管理中的重要性,并讨论此类患者继续化疗的困境。