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Effect of human lysozyme (muramidase) on potassium handling by the perfused rat kidney. A mechanism for renal damage in human monocytic leukaemia.

作者信息

Mason D Y, Howes D T, Taylor C R, Ross B D

出版信息

J Clin Pathol. 1975 Sep;28(9):722-7. doi: 10.1136/jcp.28.9.722.

DOI:10.1136/jcp.28.9.722
PMID:1058211
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC475814/
Abstract

Purified human lysozyme (muramidase) stimulated potassium excretion by the isolated perfused rat kidney. Lysozyme is filtered and reabsorbed, without a tubular maximum. Over 90% of lysozyme filtered is retained within the kidney; 50% was recovered by enzymic assay and histologically localized to the proximal tubular cells. Hypokalaemia seen in some patients with myelomonocytic leukaemia may be directly attributed to an elevated circulating lysozyme level.

摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca92/475814/6ef0c0923aed/jclinpath00143-0037-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca92/475814/b885db26f425/jclinpath00143-0036-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca92/475814/6ef0c0923aed/jclinpath00143-0037-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca92/475814/b885db26f425/jclinpath00143-0036-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca92/475814/6ef0c0923aed/jclinpath00143-0037-a.jpg

相似文献

1
Effect of human lysozyme (muramidase) on potassium handling by the perfused rat kidney. A mechanism for renal damage in human monocytic leukaemia.
J Clin Pathol. 1975 Sep;28(9):722-7. doi: 10.1136/jcp.28.9.722.
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Muramidasuria and hyperkaluria in the chloroleukemic rat.
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6
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Renal handling of low molecular weight proteins.
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Monocytic and monomyelocytic leukaemia with increased serum and urine lysozyme as a late complication in plasma cell myeloma.单核细胞性和单核粒细胞性白血病伴血清和尿溶菌酶升高，为浆细胞骨髓瘤的晚期并发症
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引用本文的文献

1
Dependence of renal protein reabsorption on glomerular filtration rate and infusion time.肾蛋白重吸收对肾小球滤过率和输注时间的依赖性。
Pflugers Arch. 1984 Sep;402(1):34-8. doi: 10.1007/BF00584828.
2
Lysozyme: a brief review.溶菌酶：简要综述。
Postgrad Med J. 1977 May;53(619):257-9. doi: 10.1136/pgmj.53.619.257.

本文引用的文献

1
EFFECT OF CATIONIC AMINO ACID INFUSION ON POTASSIUM METABOLISM IN VIVO.阳离子氨基酸输注对体内钾代谢的影响。
Am J Physiol. 1964 Feb;206:403-8. doi: 10.1152/ajplegacy.1964.206.2.403.
2
Lysozymuria induced in rats by nephrotoxic agents.
Proc Soc Exp Biol Med. 1966 Nov;123(2):380-5. doi: 10.3181/00379727-123-31494.
3
Renal tubular potassium transport.肾小管钾转运
Bull Schweiz Akad Med Wiss. 1967 Dec;23(3):287-312.
4
Quantitative immunochemical determination of lysoqyme (muramidase) in serum and urine.血清和尿液中溶菌酶（胞壁质酶）的定量免疫化学测定。
Scand J Clin Lab Invest. 1971 May;27(3):255-61. doi: 10.3109/00365517109080216.
5
Plasma muramidase: a study of methods and clinical applications.血浆溶菌酶：方法与临床应用研究
J Lab Clin Med. 1970 Jan;75(1):83-92.
6
Lysozymuria and renal tubular dysfunction in monocytic and myelomonocytic leukemia.单核细胞和粒单核细胞白血病中的溶菌酶尿症及肾小管功能障碍
Am J Med. 1969 Sep;47(3):351-66. doi: 10.1016/0002-9343(69)90219-8.
7
Serum and urinary lysozyme (muramidase) in monocytic and monomyelocytic leukemia.单核细胞性和单核粒细胞性白血病中的血清及尿液溶菌酶（胞壁质酶）
J Exp Med. 1966 Nov 1;124(5):921-52. doi: 10.1084/jem.124.5.921.
8
Clinical significance of serum and urinary muramidase activity in leukemia and other hematologic malignancies.血清和尿中溶菌酶活性在白血病及其他血液系统恶性肿瘤中的临床意义
Am J Med. 1969 Mar;46(3):330-43. doi: 10.1016/0002-9343(69)90036-9.
9
Lysozyme: antigen, enzyme and antibacterial agent.溶菌酶：抗原、酶及抗菌剂。
Sci Basis Med Annu Rev. 1968:31-52.
10
Sodium reabsorption in the perfused rat kidney.灌注大鼠肾脏中的钠重吸收。
Am J Physiol. 1973 Nov;225(5):1165-71. doi: 10.1152/ajplegacy.1973.225.5.1165.