Tsugawa K, Koyanagi N, Nakanishi K, Wada H, Tanoue K, Hashizume M, Sugimachi K
Department of Surgery II, Faculty of Medicine, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan.
Eur J Med Res. 1999 Nov 22;4(11):483-7.
Primary leiomyosarcoma of the thyroid gland is rare, and to the best of our knowledge only nine well-documented cases have been previously reported in the world literature. We herein report a 90-year-old female patient with primary leiomyosarcoma of the thyroid gland who showed a rapid tumor growth and tracheal obstruction. The patient was successfully treated by a partial resection of the thyroid gland using an ultrasonically activated scalpel and emergency tracheostomy. Immunohistochemically, the tumor cells showed positive reactivity to smooth muscle actin and negative reactivity to thyroglobin. Palliative surgery successfully allowed the patient to recover from the symptoms of dyspnea related to this rare disease. The use of an ultrasonically activated scalpel and tracheostomy thus allowed us to safely perform a thyroidectomy with substantially less bleeding than normal.
甲状腺原发性平滑肌肉瘤罕见,据我们所知,世界文献中此前仅报道过9例有充分记录的病例。我们在此报告1例90岁女性甲状腺原发性平滑肌肉瘤患者,该患者肿瘤生长迅速并导致气管梗阻。使用超声刀对甲状腺进行部分切除并实施紧急气管切开术,成功治疗了该患者。免疫组织化学检查显示,肿瘤细胞对平滑肌肌动蛋白呈阳性反应,对甲状腺球蛋白呈阴性反应。姑息性手术成功使患者从与这种罕见疾病相关的呼吸困难症状中恢复。因此,使用超声刀和气管切开术使我们能够安全地进行甲状腺切除术,出血量比正常情况少得多。