Canu G L, Bulla J S, Lai M L, Medas F, Baghino G, Erdas E, Mariotti S, Calò P G
G Chir. 2018 Jan-Feb;39(1):51-56. doi: 10.11138/gchir/2018.39.1.051.
Primary thyroid leiomyosarcoma (LMS) is an extremely rare tumor. We report a case of a 47-year-old male with a rapidly growing neck mass and disfagia. Preoperative investigations were diagnostic of anaplastic carcinoma. Total thyroidectomy with partial esophagectomy and dissection of right infrahyoid muscles was performed. Through histolological and immunohistochemical evaluations a primary thyroid high-grade LMS was diagnosed. At 2 months of follow-up a local recurrence was detected and consequently the patient was submitted to chemotherapy with partial response. He is still alive 9 months after surgery. Diagnosis of primary thyroid LMS is difficult due to its similarity to other more common thyroid tumors. To date, there is no standard therapy and prognosis is poor.
原发性甲状腺平滑肌肉瘤（LMS）是一种极其罕见的肿瘤。我们报告一例47岁男性患者，其颈部肿块迅速增大并伴有吞咽困难。术前检查诊断为未分化癌。遂行甲状腺全切除术、部分食管切除术及右侧舌骨下肌群清扫术。通过组织学和免疫组化评估，诊断为原发性甲状腺高级别LMS。随访2个月时发现局部复发，因此患者接受化疗，部分缓解。术后9个月他仍然存活。原发性甲状腺LMS的诊断因其与其他更常见的甲状腺肿瘤相似而困难。迄今为止，尚无标准治疗方法，预后较差。
