Chabaud P, Ravel N, Wilson D A, Gervais R
lnstitut des Sciences Cognitives, CNRS - UPR 9075, Bron, France.
Neurosci Lett. 1999 Nov 26;276(1):17-20. doi: 10.1016/s0304-3940(99)00773-9.
This experiment determined the importance of functional coupling between structures of central olfactory pathways: the olfactory bulb (OB), anterior (APC), posterior (PPC) parts of the piriform cortex and lateral entorhinal cortex (EC). From local field potential signals obtained in awake rats, coupling during spontaneous activity was estimated with variables reflecting level of coherence computed with a dynamical method. Results revealed a clear hierarchy in the strength of coupling between structures with dissociation within the piriform cortex: PPC was more tightly coupled with the EC than with APC. Systemic injection of a cholinergic antagonist, scopolamine, suggested that tonic coupling is strongly mediated by cortico-cortical connections and not by an external synchronizer, except between OB and APC.
嗅球（OB）、梨状皮质的前部（APC）、后部（PPC）以及外侧内嗅皮质（EC）。从清醒大鼠获得的局部场电位信号中，利用反映动态计算相干性水平的变量来估计自发活动期间的耦合。结果显示，各结构之间的耦合强度存在明显层次，梨状皮质内部存在解耦：PPC与EC的耦合比与APC的更紧密。全身性注射胆碱能拮抗剂东莨菪碱表明，除了OB和APC之间，紧张性耦合主要由皮质-皮质连接介导，而非由外部同步器介导。
