Creed F
Department of Psychological Medicine, Manchester Royal Infirmary, United Kingdom.
Am J Med. 1999 Nov 8;107(5A):74S-80S. doi: 10.1016/s0002-9343(99)00083-2.
This article reviews the evidence that psychiatric disorders have an adverse influence on the outcome of irritable bowel syndrome (IBS) and relates this to the close relationship between psychological symptoms and severity of abdominal pain, bloating, and diarrhea. Therefore, accurate measurement of psychological symptoms may be an important aspect of trial design for IBS therapy. The importance of psychological distress and health anxiety in differentiating "consulters" and "nonconsulters" for IBS is reviewed. The consequences of excluding from a trial people with certain types of psychiatric disorder or with a known past history of sexual abuse are considered.
本文综述了精神障碍对肠易激综合征（IBS）预后产生不利影响的证据，并将其与心理症状与腹痛、腹胀及腹泻严重程度之间的密切关系联系起来。因此，准确测量心理症状可能是IBS治疗试验设计的一个重要方面。本文还综述了心理困扰和健康焦虑在区分IBS“咨询者”和“非咨询者”方面的重要性。文中考虑了在试验中排除患有某些类型精神障碍或有已知性虐待既往史的人的后果。
