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[缩短的促甲状腺激素释放激素-促甲状腺激素试验与甲状腺抑制试验在甲状腺功能亢进症诊断中的比较]

[Comparison between a shortened TRH-TSH test and thyroid suppression test in the diagnosis of hyperthyroidosis].

作者信息

Müller J, Závada M, Kuchar O

出版信息

Endokrinologie. 1978 Nov;72(3):354-62.

PMID:105902
Abstract

In a selected group of fifty-one persons suspected to be hyperthyroid the comparison between a shortened variant of TRH-TSH stimulation test and thyroid suppression test was made. In patients whose other functional tests gave no univocal results, the agreement between suppressibility of radioiodine uptake and TSH response in 90,2% of cases could be established. High degree of correlation between both parameters (coefficient V = 0.791) permits to regard these tests as practically equivaluablein giving evidence of dysregulation between pituitary and thyroid gland. In persons with TSH-dependent thyroid function, however, no correlation between numerical values of radioiodine uptake and TSH concentrations after stimulations was found.

摘要

在一组选定的51名疑似甲状腺功能亢进的患者中,对促甲状腺激素释放激素(TRH)-促甲状腺激素(TSH)刺激试验的缩短变体与甲状腺抑制试验进行了比较。在其他功能试验结果不明确的患者中,90.2%的病例放射性碘摄取抑制率与TSH反应之间存在一致性。两个参数之间的高度相关性(相关系数V = 0.791)使得可以认为这些试验在证明垂体与甲状腺之间的调节异常方面实际上是等效的。然而,在促甲状腺激素依赖性甲状腺功能的患者中,刺激后放射性碘摄取数值与TSH浓度之间未发现相关性。

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