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1
A mechanism for initiation of genetic recombination.一种基因重组起始的机制。
Proc Natl Acad Sci U S A. 1975 Sep;72(9):3619-22. doi: 10.1073/pnas.72.9.3619.
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Nick-free formation of reciprocal heteroduplexes: a simple solution to the topological problem.无镍形成相互异源双链体：拓扑问题的简单解决方案。
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Inversion/dimerization of plasmids mediated by inverted repeats.由反向重复序列介导的质粒反向/二聚化
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引用本文的文献

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Model for the participation of quasi-palindromic DNA sequences in frameshift mutation.准回文DNA序列参与移码突变的模型。
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6
Mitotic recombination in yeast: isolation and characterization of mutants with enhanced spontaneous mitotic gene conversion rates.酵母中的有丝分裂重组：自发有丝分裂基因转换率增强的突变体的分离与鉴定
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7
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8
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9
Illegitimate recombination generates a class switch from C mu to C delta in an IgD-secreting plasmacytoma.在一个分泌IgD的浆细胞瘤中，非法重组导致了从Cμ到Cδ的类别转换。
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A DNA-unwinding protein isolated from Escherichia coli: its interaction with DNA and with DNA polymerases.从大肠杆菌中分离出的一种DNA解旋蛋白：它与DNA及DNA聚合酶的相互作用。
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一种基因重组起始的机制。

A mechanism for initiation of genetic recombination.

作者信息

Wagner R E, Radman M

出版信息

Proc Natl Acad Sci U S A. 1975 Sep;72(9):3619-22. doi: 10.1073/pnas.72.9.3619.

DOI:10.1073/pnas.72.9.3619
PMID:1059151
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC433047/
Abstract

A mechanism for the initiation of genetic recombination is proposed. Its key features are the pairing, nicking, and cross-annealing of palindromic loops, i.e., structures formed by DNA with sequences of inverted complementary repeats. This mechanism may provide a simple, yet specific means of producing crossed strand connections between homologous DNA duplexes to form structures which can be intermediates in the process of genetic recombination.

摘要

提出了一种基因重组起始机制。其关键特征是回文环的配对、切口和交叉退火，即由具有反向互补重复序列的DNA形成的结构。该机制可能提供一种简单而特异的方式，在同源DNA双链体之间产生交叉链连接，以形成可作为基因重组过程中间体的结构。