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果蝇肌纤维中的自发连接电流:温度、膜电位和乙醇的影响

Spontaneous junctional currents in Drosophila muscle fibres: effects of temperature, membrane potential and ethanol.

作者信息

Magazanik L G, Vyskocil F

出版信息

Experientia. 1979 Feb 15;35(2):213-4. doi: 10.1007/BF01920623.

DOI:10.1007/BF01920623
PMID:105927
Abstract

Fast, slow and fast multiquantal spontaneous junctional currents were recorded from glutamate sensitive muscle fibres of Drosophila larvae. Decrease of temperature and hyperpolarization prolonged the time course of fast currents. Ethanol (0.4 M) markedly shortened their duration, whereas several other drugs known to modify the time course of currents at cholinergic synapses were ineffective at this neuromuscular junction.

摘要

在果蝇幼虫对谷氨酸敏感的肌纤维上记录到了快速、慢速和快速多量子自发接头电流。温度降低和超极化延长了快速电流的时程。乙醇(0.4 M)显著缩短了它们的持续时间,而其他几种已知可改变胆碱能突触处电流时程的药物在这个神经肌肉接头处却无效。

相似文献

1
Spontaneous junctional currents in Drosophila muscle fibres: effects of temperature, membrane potential and ethanol.果蝇肌纤维中的自发连接电流:温度、膜电位和乙醇的影响
Experientia. 1979 Feb 15;35(2):213-4. doi: 10.1007/BF01920623.
2
[Synaptic ion currents in muscle fibers of Drosophila melanogaster].[黑腹果蝇肌肉纤维中的突触离子电流]
Zh Evol Biokhim Fiziol. 1978 Sep-Oct;14(5):448-52.
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[Postsynaptic ionic endplate currents of fast and slow chick muscle fibers. Effect of cholinesterase inhibition].
Neirofiziologiia. 1981;13(4):390-7.
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Miniature endplate currents at the newly formed neuromuscular junction in Drosophila embryos and larvae.果蝇胚胎和幼虫中新形成的神经肌肉接头处的微小终板电流。
Neurosci Res. 1994 Mar;19(2):143-54. doi: 10.1016/0168-0102(94)90137-6.
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A voltage clamp study of the glutamate responsive neuromuscular junction in Drosophila melanogaster.黑腹果蝇中谷氨酸反应性神经肌肉接头的电压钳研究。
Can J Physiol Pharmacol. 1988 Apr;66(4):321-7. doi: 10.1139/y88-055.
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[Comparison of the action of hyperpolarization and ethanol on frog end-plate currents at different cholinoceptor densities].[超极化与乙醇对不同胆碱能受体密度下青蛙终板电流作用的比较]
Neirofiziologiia. 1988;20(1):128-30.
7
The time course of miniature endplate currents and its modification by receptor blockade and ethanol.微小终板电流的时间进程及其受受体阻断和乙醇的影响。
J Gen Physiol. 1984 Mar;83(3):435-68. doi: 10.1085/jgp.83.3.435.
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[Effect of neurotoxins on mediator release from the motor nerve endings of the Drosophila melanogaster larva].
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[Miniature end-plate currents of slow and fast extraocular muscle fibres of the guinea pig].
Sheng Li Xue Bao. 1987 Aug;39(4):334-42.
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[Features of the postsynaptic potentials and ion currents in synapses of fast and slow rat muscle fibers].[大鼠快、慢肌纤维突触后电位和离子电流的特征]
Neirofiziologiia. 1980;12(6):627-36.

引用本文的文献

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Physiol Res. 2024 Aug 30;73(S1):S83-S103. doi: 10.33549/physiolres.935414. Epub 2024 Jul 2.
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Blockade of ion channels as an approach to studying AMPA receptor subtypes.作为研究AMPA受体亚型的一种方法的离子通道阻断
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3
Postsynaptic actions of ethanol and methanol in crayfish neuromuscular junctions.乙醇和甲醇在小龙虾神经肌肉接头处的突触后作用。

本文引用的文献

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Proceedings: Factors affecting the time course of decay of excitatory post-synaptic currents at a glutamate synapse.论文集:影响谷氨酸突触处兴奋性突触后电流衰减时间进程的因素
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