Urbach D R, Rotstein O D
Department of Surgery, The Toronto Hospital and the University of Toronto.
Can J Surg. 1999 Dec;42(6):415-9.
To provide an overview of the pathophysiological features and management of the clinical entity typhlitis.
The data presented are derived from a review of the English-language literature on typhlitis. The majority of papers analysed were small clinical series.
Data derived from the literature review were collated. The major finding was that typhlitis comprises a number of different diseases characterized by the presence of right lower quadrant pain, an immunocompromised host and altered function of the mucosal barrier of the right colon.
Typhlitis should be suspected in any immunocompromised patient presenting with right lower quadrant pain with compatible radiographic findings. Most patients can be treated conservatively with intravenously administered fluids and antibiotics, although surgery may be necessary if complications arise.
概述盲肠炎这一临床病症的病理生理特征及治疗方法。
所呈现的数据源自对关于盲肠炎的英文文献的综述。分析的大多数论文为小型临床系列研究。
对文献综述得出的数据进行了整理。主要发现是，盲肠炎包含多种不同疾病，其特征为右下象限疼痛、免疫功能低下宿主以及右半结肠黏膜屏障功能改变。
对于任何出现右下象限疼痛且影像学检查结果相符的免疫功能低下患者，均应怀疑患有盲肠炎。大多数患者可通过静脉补液和使用抗生素进行保守治疗，不过若出现并发症则可能需要手术治疗。
