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罕见病常见问题组合:一名慢性髓性白血病患者的右下腹疼痛

Combination of Common Problem in a Rare Disease: Right Iliac Fossa Pain in a Chronic Myeloid Leukemia Patient.

作者信息

Ramzee Ahmed Faidh, Sameer Mohammad, Khan Mohammad Burhan, Muhammad Ali Syed, Zarour Ahmad

机构信息

Surgery, Hamad Medical Corporation, Doha, QAT.

Acute Care Surgery, Hamad Medical Corporation, Doha, QAT.

出版信息

Cureus. 2020 Nov 17;12(11):e11523. doi: 10.7759/cureus.11523.

DOI:10.7759/cureus.11523
PMID:33354467
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7746320/
Abstract

Abdominal symptoms in patients with hematological malignancies can occur due to an array of pathologies. Two diagnoses with similar presentation albeit, generally opposite treatment modalities, are typhlitis (inflammation of cecum) and acute appendicitis. Both diagnoses have to be kept in mind in such a patient presenting with right lower quadrant (RLQ) pain. Sagacious clinical judgment along with the aid of radiological imaging may help in differentiating between the two conditions. We present a case of a young male with chronic myeloid leukemia (CML) on imatinib, diagnosed and started on therapy four years earlier, who presented with symptoms of RLQ pain not typical of acute appendicitis. The accurate diagnosis was made with the assistance of ultrasound (US) imaging and prompt surgical therapy was instituted followed by a smooth postoperative recovery.

摘要

血液系统恶性肿瘤患者的腹部症状可能由一系列病理情况引起。盲肠炎(盲肠炎症)和急性阑尾炎这两种诊断表现相似,但治疗方式通常相反。对于出现右下腹(RLQ)疼痛的此类患者,必须同时考虑这两种诊断。明智的临床判断以及放射影像学检查有助于区分这两种情况。我们报告一例年轻男性慢性髓系白血病(CML)患者,服用伊马替尼,4年前确诊并开始治疗,此次出现并非典型急性阑尾炎的右下腹疼痛症状。借助超声(US)成像做出了准确诊断,并立即进行了手术治疗,术后恢复顺利。

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1
Combination of Common Problem in a Rare Disease: Right Iliac Fossa Pain in a Chronic Myeloid Leukemia Patient.罕见病常见问题组合:一名慢性髓性白血病患者的右下腹疼痛
Cureus. 2020 Nov 17;12(11):e11523. doi: 10.7759/cureus.11523.
2
Faecal retention: a common cause in functional bowel disorders, appendicitis and haemorrhoids--with medical and surgical therapy.粪便潴留:功能性肠病、阑尾炎和痔疮的常见病因——兼论内科及外科治疗
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Typhlitis: A Rare Appendicitis Mimic in a Young Healthy Female.盲肠炎:年轻健康女性中罕见的类阑尾炎病症
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Bol Asoc Med P R. 2011 Jan-Mar;103(1):51-3.
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Acute appendicitis in children with leukemia and other malignancies: still a diagnostic dilemma.白血病及其他恶性肿瘤患儿的急性阑尾炎:仍是诊断难题。
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Stump appendicitis. A case report.残端阑尾炎。病例报告。
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Typhlitis; is it just in immunocompromised patients?盲肠炎;它仅见于免疫功能低下的患者吗?
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引用本文的文献

1
Neutropenic Enterocolitis in a Patient With Acute Myeloid Leukemia.一名急性髓系白血病患者的中性粒细胞减少性小肠结肠炎
Cureus. 2022 Jul 10;14(7):e26712. doi: 10.7759/cureus.26712. eCollection 2022 Jul.

本文引用的文献

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Timing and Outcomes of Abdominal Surgery in Neutropenic Patients.中性粒细胞减少症患者腹部手术的时机和结果。
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Ultrasound diagnosis of typhlitis.盲肠炎的超声诊断
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Neutropenic enterocolitis.中性粒细胞减少性小肠结肠炎
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Diagnosis, incidence, and outcomes of suspected typhlitis in oncology patients--experience in a tertiary pediatric surgical center in the United Kingdom.肿瘤患者疑似盲肠炎的诊断、发病率及预后——英国一家三级儿科外科中心的经验
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