（N-巴比妥基）苯基和环己基链烷酸及其某些衍生物作为潜在的抗炎剂。
(N-Barbituryl)phenyl- and cyclohexylalkanoic acids and some of their derivatives as potential anti-inflammatory agents.
作者信息
Stankiewicz K, Bobrański B
出版信息
Farmaco Sci. 1978 Oct;33(10):729-39.
PMID:105934
Abstract
A series of p-(N-barbituryl)phenyl- and cyclohexylalkanoic acids and their esters were synthesized. The preliminary pharmacological screening using the carrageenin, xylene and cotton tests revealed strong anti-inflammatory activity of several compounds in some of the tests performed, compound (Ij) being active in all the tests.
摘要
合成了一系列对-(N-巴比妥基)苯基和环己基链烷酸及其酯。使用角叉菜胶、二甲苯和棉球试验进行的初步药理筛选显示，在进行的一些试验中，几种化合物具有很强的抗炎活性，化合物(Ij)在所有试验中均有活性。
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