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顽固性及稳定期白癜风的吸引水疱表皮移植与打孔植皮对比研究

Suction blister epidermal grafting versus punch skin grafting in recalcitrant and stable vitiligo.

作者信息

Gupta S, Jain V K, Saraswat P K

机构信息

Department of Dermatology, Rohtak, Haryana, India.

出版信息

Dermatol Surg. 1999 Dec;25(12):955-8. doi: 10.1046/j.1524-4725.1999.99069.x.

Abstract

BACKGROUND

Among various surgical therapies for replenishment of melanocytes in recalcitrant and stable vitiligo, punch skin grafting (PSG) and suction blister epidermal grafting (SBEG) are the simplest ones. Literature is lacking on a comparison of both.

OBJECTIVE

We compared the results of both techniques in small patches of vitiligo.

METHODS

Fifty stable vitiligo (focal, segmental, and generalized) patients were selected for study. One patient was lost to follow-up and excluded. PSG was done in 48 patches of 25 patients and SBEG was done in 38 patches of 24 patients. All patients were kept on psoralen ultraviolet-A (PUVA)/psoralen sunrays (PUVASOL). Results were evaluated after a follow-up of 4-7 months.

RESULTS

Thirty-two (67%) patches of the PSG group and 31 (82%) patches of the SBEG group showed greater than 75% pigmentation. The difference in both groups was not statistically significant. Cobblestone appearance (23%) over the recipient area (RA) and superficial scarring of the donor area (DA) (100%) were seen in PSG. No serious complications were seen in both groups.

CONCLUSION

Both techniques are simple and effective, however, SBEG gives cosmetically better and rapid results.

摘要

背景

在用于顽固性稳定型白癜风黑素细胞补充的各种外科治疗方法中,钻孔皮肤移植术(PSG)和水疱表皮抽吸移植术(SBEG)是最简单的方法。目前缺乏关于这两种方法比较的文献。

目的

我们比较了这两种技术治疗小片白癜风的效果。

方法

选择50例稳定型白癜风(局限性、节段性和泛发性)患者进行研究。1例患者失访并被排除。25例患者的48处皮损采用PSG治疗,24例患者的38处皮损采用SBEG治疗。所有患者均接受补骨脂素紫外线A(PUVA)/补骨脂素日光(PUVASOL)治疗。随访4 - 7个月后评估结果。

结果

PSG组32处(67%)皮损和SBEG组31处(82%)皮损色素沉着超过75%。两组差异无统计学意义。PSG可见受区(RA)出现鹅卵石样外观(23%)和供区(DA)浅表瘢痕形成(100%)。两组均未出现严重并发症。

结论

两种技术均简单有效,然而,SBEG在美容效果上更好且见效更快。

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