Babu Aravind, Thappa Devinder Mohan, Jaisankar Telanseri J
Department of Dermatology and STD, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Pondicherry, India.
Dermatol Surg. 2008 Feb;34(2):166-78; discussion 178. doi: 10.1111/j.1524-4725.2007.34034.x. Epub 2007 Dec 17.
Among surgical methods, punch skin grafting (PSG) and suction blister epidermal grafting (SBEG) are simple, inexpensive, and effective treatment methods for resistant lip vitiligo cases, but there is a lack of comparison between these procedures for lip vitiligo.
The objective was to compare the outcome following PSG and SBEG in stable lip vitiligo.
Eighteen patients with stable lip vitiligo were randomly selected. Eight patients were included in PSG group and 10 patients in SBEG. All patients were kept on PUVA-SOL (psoralen+ultraviolet A therapy of solar origin) treatment after grafting. The results were evaluated after a follow-up period of 6 months.
At the end of 6 months of grafting in PSG group, two patients had a repigmentation of 50% to 75%, one had 75% to 90%, and three had 90% to 100% in the recipient site in lip. In SBEG group, one patient had repigmentation of 50% to 75%, three had 75% to 90%, and two had 90% to 100%. The color match was statistically significant in PSG when compared to SBEG. In the recipient site, cobblestone appearance was the predominant complication in PSG whereas hyperpigmentation and thickening of grafts were common in SBEG. In the donor site, superficial scarring and hypopigmentation were the common findings in PSG group whereas hyperpigmentation was the main problem in SBEG group.
Although both the procedures are effective in lip vitiligo, PSG gives a better color match than SBEG.
在外科治疗方法中，冲孔植皮术（PSG）和吸疱表皮移植术（SBEG）是治疗顽固性唇部白癜风的简单、廉价且有效的方法，但对于唇部白癜风，这两种手术方法之间缺乏比较。
比较PSG和SBEG治疗稳定期唇部白癜风的效果。
随机选取18例稳定期唇部白癜风患者。PSG组纳入8例患者，SBEG组纳入10例患者。所有患者术后均接受PUVA-SOL（补骨脂素+源于太阳的紫外线A疗法）治疗。随访6个月后评估结果。
PSG组植皮6个月后，唇部受区有2例患者色素恢复50%至75%，1例恢复75%至90%，3例恢复90%至100%。SBEG组有1例患者色素恢复50%至75%，3例恢复75%至90%，2例恢复90%至100%。与SBEG相比，PSG的颜色匹配具有统计学意义。在受区，PSG的主要并发症是鹅卵石样外观，而SBEG常见的是色素沉着和移植皮片增厚。在供区，PSG组常见浅表瘢痕和色素减退，而SBEG组的主要问题是色素沉着。
虽然两种手术方法对唇部白癜风均有效，但PSG在颜色匹配方面优于SBEG。
