Kar Bikash R, Raj Chinmoy
Department of Dermatology, Venereology and Leprosy (DVL), Institute of Medical Sciences and SUM Hospital, Siksha 'O'Anusandhan University, Bhubaneswar, Odisha, India.
J Cutan Aesthet Surg. 2018 Jan-Mar;11(1):13-19. doi: 10.4103/JCAS.JCAS_111_15.
Lip vitiligo is usually resistant to medical modalities of treatment, and in all these cases, surgery offers a hope. Suction blister grafting (SBG) has been tried since long for lip vitiligo with high rate of success. There have been no long-term follow-up studies of patients with SBG at a difficult-to-treat site like angles of lip, which prompted us to conduct this study.
To assess the pigmentation rate and patient satisfaction of SBG on vitiligo involving angles of lip.
This is a prospective study conducted on 112 patients with stable vitiligo involving angles of lip. SBG was carried out in all the patients using the standard procedure. Patients were advised to apply topical psoralen followed by sun exposure (PUVASOL) for 8-12 weeks after operation. The patients were followed up at 3, 6, 12, 18, and 24 months for assessment of pigmentation and overall satisfaction.
We found a pigmentation success rate of 83.7%, 84.9%, 85.7%, 78.3%, and 77.8% in the patients who were followed up at 3, 6, 12, 18, and 24 months, respectively. A total of 77.8% of patients who came for follow-up at the end of 24 months were very happy with the treatment.
Our data show clearance of vitiligo and persistence of pigmentation gained through SBG in 77.8% of cases at the end of 2 years as well as excellent patient satisfaction in the cohort of patients who followed up with us.
SBG is an easy and cost-effective way of repigmentation of vitiligo involving angles of lip.
唇部白癜风通常对药物治疗有抵抗性，在所有这些情况下，手术提供了一线希望。长期以来，负压吸疱移植术（SBG）一直用于唇部白癜风的治疗，成功率较高。对于像唇角这样难以治疗的部位接受SBG治疗的患者，尚未有长期随访研究，这促使我们开展此项研究。
评估SBG治疗唇角白癜风的色素沉着率及患者满意度。
这是一项针对112例稳定期唇角白癜风患者的前瞻性研究。所有患者均采用标准程序进行SBG治疗。建议患者术后应用外用补骨脂素并接受日光照射（PUVASOL）8 - 12周。在3、6、12、18和24个月对患者进行随访，以评估色素沉着情况及总体满意度。
我们发现，在3、6、12、18和24个月进行随访的患者中，色素沉着成功率分别为83.7%、84.9%、85.7%、78.3%和77.8%。在24个月随访结束时前来复诊的患者中，共有77.8%对治疗非常满意。
我们的数据显示，在2年结束时，77.8%的病例通过SBG实现了白癜风清除及色素沉着持续存在，并且在我们随访的患者队列中患者满意度极高。
SBG是一种用于唇角白癜风色素再生的简便且经济有效的方法。
