Fröhlich H
Proc Natl Acad Sci U S A. 1975 Nov;72(11):4211-5. doi: 10.1073/pnas.72.11.4211.
From very general theoretical considerations it is concluded that many biomolecules (i) should have metastable excited states with very high dipole moment, and (ii) should be capable of strongly excited giant dipole vibrations with frequencies near 10(11) Hz. Experimental evidence available so far seems to support these postulates. It is suggested that the two postulates should be of importance for the action of enzymes, and relevant experiments are proposed.
从非常一般的理论考虑可以得出结论,许多生物分子:(i)应该具有偶极矩非常高的亚稳态激发态,并且(ii)应该能够强烈激发频率接近10^11Hz的巨大偶极振动。目前可得的实验证据似乎支持这些假设。有人提出,这两个假设对于酶的作用应该是重要的,并提出了相关实验。