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The extraordinary dielectric properties of biological materials and the action of enzymes.生物材料的非凡介电特性及酶的作用。
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本文引用的文献

1
Dielectric dispersion in bovine serum albumen.牛血清白蛋白中的介电色散。
J Mol Biol. 1966 Aug;19(1):133-9. doi: 10.1016/s0022-2836(66)80055-4.
2
Dielectric properties of hemoglobin and myoglobin. II. Dipole moment of sperm whale myoglobin.
Biopolymers. 1969;8(6):757-65. doi: 10.1002/bip.1969.360080606.
3
Hydration of proteins and polypeptides.蛋白质和多肽的水合作用。
Adv Protein Chem. 1974;28:239-345. doi: 10.1016/s0065-3233(08)60232-6.
4
Conformationally dependent low-frequency motions of proteins by laser Raman spectroscopy.利用激光拉曼光谱研究蛋白质的构象依赖性低频运动。
Proc Natl Acad Sci U S A. 1972 Jun;69(6):1467-9. doi: 10.1073/pnas.69.6.1467.
5
Long-lived conformation changes induced by electric impulses in biopolymers.生物聚合物中电脉冲诱导的长寿命构象变化。
Proc Natl Acad Sci U S A. 1972 Apr;69(4):993-7. doi: 10.1073/pnas.69.4.993.

生物材料的非凡介电特性及酶的作用。

The extraordinary dielectric properties of biological materials and the action of enzymes.

作者信息

Fröhlich H

出版信息

Proc Natl Acad Sci U S A. 1975 Nov;72(11):4211-5. doi: 10.1073/pnas.72.11.4211.

DOI:10.1073/pnas.72.11.4211
PMID:1060101
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC388689/
Abstract

From very general theoretical considerations it is concluded that many biomolecules (i) should have metastable excited states with very high dipole moment, and (ii) should be capable of strongly excited giant dipole vibrations with frequencies near 10(11) Hz. Experimental evidence available so far seems to support these postulates. It is suggested that the two postulates should be of importance for the action of enzymes, and relevant experiments are proposed.

摘要

从非常一般的理论考虑可以得出结论,许多生物分子:(i)应该具有偶极矩非常高的亚稳态激发态,并且(ii)应该能够强烈激发频率接近10^11Hz的巨大偶极振动。目前可得的实验证据似乎支持这些假设。有人提出,这两个假设对于酶的作用应该是重要的,并提出了相关实验。