犬骨肉瘤的核型，来自原发肿瘤、其转移灶以及组织培养中的肿瘤细胞。
Canine osteosarcoma karyotypes from an original tumor, its metastasis, and tumor cells in tissue culture.
作者信息
Taylor N, Shifrine M, Wolf H G, Trommershausen-Smith A
出版信息
Transplant Proc. 1975 Dec;7(4):485-93.
Radiation-induced osteosarcoma, its metastasis, and cells grown in tissue culture were karyotyped. Both hypodiploid and hyperdiploid stem lines were observed. The hypodiploid line contained 45-55 chromosomes with 10-15 abnormal metacentric and submetacentric chromosomes and one subtelocentric marker. The hyperdiploid line contained 90-105 chromosomes with 20-30 abnormal metacentric and submetacentric chromosomes with two subtelocentric markers. Karyotypic analysis can be used to monitor osteosarcomas maintained in tissue culture.
对辐射诱发的骨肉瘤、其转移灶以及在组织培养中生长的细胞进行了核型分析。观察到了亚二倍体和超二倍体干细胞系。亚二倍体系含有45 - 55条染色体，其中有10 - 15条异常的中着丝粒和亚中着丝粒染色体以及一个亚端着丝粒标记。超二倍体系含有90 - 105条染色体，其中有20 - 30条异常的中着丝粒和亚中着丝粒染色体以及两个亚端着丝粒标记。核型分析可用于监测组织培养中保存的骨肉瘤。
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