Tranquart F, Arsene S, Giraudeau B, Piquemal R, Eder V, Le Lez M L, Rossazza C, Pourcelot L
Nuclear Medicine and Ultrasound Department, Centre Hospitalier Universitaire Bretonneau, 37044 Tours Cedex 1, France.
J Clin Ultrasound. 2000 Jan;28(1):28-33. doi: 10.1002/(sici)1097-0096(200001)28:1<28::aid-jcu4>3.0.co;2-5.
We assessed early hemodynamic characteristics of various types of retinal vein occlusion using color Doppler imaging and spectral analysis.
We measured the maximum systolic and diastolic blood flow velocities and the resistance index (RI) in the central retinal artery and the maximum and minimum blood flow velocities in the central retinal vein of affected eyes and contralateral unaffected eyes in 102 adults (63 men and 39 women; mean age, 61 +/- 14.6 years) who presented with retinal vein occlusion. Sixty-three control subjects (27 men and 36 women; mean age, 50 +/- 22.1 years) were also investigated.
No significant differences in hemodynamic characteristics were found between the control subjects' eyes and the patients' unaffected eyes. In the 18 cases of ischemic central retinal vein occlusion, the mean diastolic arterial flow velocity (p = 0.005) and venous flow velocity (p < 0.04) were lower and the mean RI was higher (p = 0. 0002) in the affected eyes than in the unaffected contralateral eyes. In the 51 cases of nonischemic central retinal vein occlusion, the mean diastolic arterial flow velocity (p < 0.0001) and venous flow velocity (p < 0.0001) also were lower and the mean RI (p < 0.0001) was higher in the affected eyes than in the unaffected contralateral eyes. These variables were different in the ischemic versus nonischemic types of central retinal vein occlusion. In the 33 cases of branch retinal vein occlusion, no significant differences were observed in arterial or venous blood flow velocities in the affected versus unaffected eyes. The mean RI in the affected eyes was significantly higher (p = 0.009) in patients with central versus branch retinal vein occlusion.
These results suggest that previous arterial disorders were not involved in the pathogenesis of central retinal vein occlusion in these patients. The findings also support the value of Doppler imaging and spectral analysis in the diagnosis and evaluation of retinal vein occlusion and confirm the involvement of arterial flow in venous occlusion.
我们使用彩色多普勒成像和频谱分析评估了各种类型视网膜静脉阻塞的早期血流动力学特征。
我们测量了102例视网膜静脉阻塞成人患者（63例男性和39例女性；平均年龄61±14.6岁）患眼及对侧未患眼的视网膜中央动脉的最大收缩期和舒张期血流速度以及阻力指数（RI），以及视网膜中央静脉的最大和最小血流速度。还对63名对照受试者（27例男性和36例女性；平均年龄50±22.1岁）进行了研究。
对照受试者的眼睛与患者的未患眼之间在血流动力学特征方面未发现显著差异。在18例缺血性中央视网膜静脉阻塞中，患眼的平均舒张期动脉血流速度（p = 0.005）和静脉血流速度（p < 0.04）较低，平均RI较高（p = 0.0002），高于对侧未患眼。在51例非缺血性中央视网膜静脉阻塞中，患眼的平均舒张期动脉血流速度（p < 0.0001）和静脉血流速度（p < 0.0001）也较低，平均RI（p < 0.0001）较高，高于对侧未患眼。这些变量在缺血性与非缺血性中央视网膜静脉阻塞类型中有所不同。在33例视网膜分支静脉阻塞中，患眼与未患眼的动脉或静脉血流速度未观察到显著差异。中央视网膜静脉阻塞患者患眼的平均RI显著高于视网膜分支静脉阻塞患者（p = 0.009）。
这些结果表明，先前的动脉疾病与这些患者中央视网膜静脉阻塞的发病机制无关。这些发现还支持了多普勒成像和频谱分析在视网膜静脉阻塞诊断和评估中的价值，并证实了动脉血流参与静脉阻塞。
