在发作性睡病患者中，主观嗜睡评分（爱泼沃斯嗜睡量表）所反映的嗜睡参数与客观嗜睡（清醒度维持测试）并不相同。

Subjective sleepiness ratings (Epworth sleepiness scale) do not reflect the same parameter of sleepiness as objective sleepiness (maintenance of wakefulness test) in patients with narcolepsy.

作者信息

Sangal R B, Mitler M M, Sangal J M

机构信息

Sleep Disorders Institute and Sangal Research Foundation, Troy, MI, USA.

出版信息

Clin Neurophysiol. 1999 Dec;110(12):2131-5. doi: 10.1016/s1388-2457(99)00167-4.

DOI:10.1016/s1388-2457(99)00167-4

PMID:10616118

Abstract

OBJECTIVE

To evaluate whether subjective (Epworth Sleepiness Scale or ESS) and objective (Maintenance of Wakefulness Test or MWT) tests of sleepiness are equally useful in patients with narcolepsy.

METHODS

Correlational study evaluating the relationship between ESS and MWT as measures of sleepiness.

SETTING

Multi-center.

PATIENTS

522 patients (17-68 year old men and women) with a current diagnosis of narcolepsy.

INTERVENTIONS

None.

RESULTS

Correlations were: MSLT and MWT, r = 0.52 (P<0.001); MWT and ESS, r = -0.29 (P<0.001); MSLT and ESS, r = -0.27 (P<0.001). Regression curve estimation using linear and curvilinear models revealed no difference among linear and curvilinear models between MWT and MSLT, and between MSLT and ESS. However, curvilinear models were better at explaining the relationship between MWT and ESS, with the cubic model being the best. As the level of severe sleepiness (as measured by the MWT) changed, the ESS remained stable.

CONCLUSIONS

In a large narcolepsy sample, the MWT and ESS are not equally useful, and do not measure the same parameter of sleepiness.

摘要

目的

评估嗜睡的主观测试（爱泼沃斯思睡量表或ESS）和客观测试（清醒维持试验或MWT）在发作性睡病患者中是否同样有用。

方法

进行相关性研究，评估ESS与MWT作为嗜睡测量指标之间的关系。

设置

多中心。

患者

522例目前诊断为发作性睡病的患者（年龄在17 - 68岁之间的男性和女性）。

干预措施

无。

结果

相关性如下：多导睡眠图（MSLT）与MWT，r = 0.52（P<0.001）；MWT与ESS，r = -0.29（P<0.001）；MSLT与ESS，r = -0.27（P<0.001）。使用线性和曲线模型进行回归曲线估计显示，MWT与MSLT之间以及MSLT与ESS之间的线性和曲线模型没有差异。然而，曲线模型在解释MWT与ESS之间的关系方面更好，三次模型是最好的。随着严重嗜睡程度（通过MWT测量）的变化，ESS保持稳定。