Jiménez-Correa Ulises, Haro Reyes, Obdulia González Rosa, Velázquez-Moctezuma Javier
Clínica de Trastornos de Sueño, Facultad de Medicina, Universidad Nacional Autónoma de México, Distrito Federal, México.
Arq Neuropsiquiatr. 2009 Dec;67(4):995-1000. doi: 10.1590/s0004-282x2009000600006.
To determine the correlations between excessive daytime sleepiness (EDS), assessed by the Epworth sleepiness scale (ESS), and the multiple sleep latency test (MSLT) and nocturnal sleep architecture features, clinical symptoms of narcolepsy (CSN) and subjective sleep quality (SSQ) in patients with narcolepsy.
Twenty three untreated patients were studied and compared with a matched control group. Diagnosis of narcolepsy was carried out employing a clinical interview, a polysomnographic (PSG) record, and an MSLT.
Subjective number of awakenings was the SSQ indicator that best correlated with EDS (ESS and MSLT). Regarding clinical features, diurnal tiredness and sleep paralysis correlated with ESS values. Increase in ESS was related with decrease in total sleep time, SWS, and sleep onset latency. On the other hand, increase in MSLT was related with decrease in SWS.
These data suggest that EDS in patients with narcolepsy could be impaired by disturbed nocturnal sleep.
通过爱泼沃斯思睡量表（ESS）评估发作性睡病患者日间过度嗜睡（EDS）与多次睡眠潜伏期试验（MSLT）、夜间睡眠结构特征、发作性睡病临床症状（CSN）及主观睡眠质量（SSQ）之间的相关性。
对23例未经治疗的患者进行研究，并与匹配的对照组进行比较。采用临床访谈、多导睡眠图（PSG）记录和MSLT进行发作性睡病的诊断。
主观觉醒次数是与EDS（ESS和MSLT）相关性最好的SSQ指标。在临床特征方面，日间疲劳和睡眠瘫痪与ESS值相关。ESS升高与总睡眠时间、慢波睡眠（SWS）和睡眠起始潜伏期缩短有关。另一方面，MSLT增加与SWS减少有关。
这些数据表明，发作性睡病患者的EDS可能因夜间睡眠紊乱而受损。
